rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Ionizing Radiation and the Immune Response - Part B
  name:
    name part: Galluzzi, Lorenzo.
    role:
      role term: creator
  name:
    name part: Mirjolet, Celine.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: cau
    date issued: 2023
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (290 pages).
  abstract: This volume, part of the International Review of Cell and Molecular Biology series, delves into the intersection of ionizing radiation and the immune response. It explores the dual impact of radiation therapy on immune responses, focusing on radio-induced lymphopenia and the integration of radiotherapy with natural killer (NK) cell-based therapies. The book examines the role of dendritic cells and the effects of targeted radionuclide therapy, alongside the opportunities and challenges of using low-dose radiation to enhance immunotherapy efficacy. It also covers recent advances in targeting suppressor cells within radiotherapy contexts. Edited by Celine Mirjolet and Lorenzo Galluzzi, the book is intended for researchers and professionals in oncology and immunotherapy, providing insights into the latest developments and applications in the field.
  table of contents: Front Cover -- Ionizing Radiation and the Immune Response -- Part B -- Copyright -- Contents -- Contributors -- Dual impact of radiation therapy on tumor-targeting immune responses -- Acknowledgments -- Competing interests -- References -- Chapter One: Radio-induced lymphopenia in the era of anti-cancer immunotherapy -- 1. Introduction -- 2. Radio-induced lymphopenia (RIL) -- 2.1. Clinical definition -- 2.2. Incidence and therapeutic implications of RIL -- 2.3. Prognostic factors for RIL -- 3. Dynamics of RIL -- 3.1. Depletion phase -- 3.2. Remission phase -- 4. RIL in the era of immunotherapies -- 4.1. Lymphopenia as a poor prognostic factor of outcome in combined radiotherapy/immunotherapy treatments -- 4.2. Synergistic mechanisms -- 4.3. Radiotherapy and immunotherapy combination in clinics -- 5. How to implement efficient lymphocyte sparing radiotherapy? -- 6. Conclusion -- Acknowledgments -- References -- Chapter Two: Combining radiotherapy and NK cell-based therapies: The time has come -- 1. Introduction -- 2. Radiation therapy can improve the NK cell-mediated anti-tumor response -- 2.1. NK expansion and activation depending on dose and fractionation
  subject:
    topic: Radiotherapy
  subject:
    topic: Immune response
  classification: QR186 .G355 2023
  classification: 363.1799
  related item:
    title info:
      title: Issn Series
  identifier: 0443184321
  identifier: 9780443184321
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: SFB
    record creation date: 230714
    record change date: 20260327174729.9
    record identifier: in00005772075
    language of cataloging:
      language term: eng