Profiles of drug substances, excipients, and related methodology. Volume 48 /

"The profiling of drug substances and excipients has become an invaluable tool for the pharmaceutical analyst in his quest for the best quality analytical data. Volume 48 contains five profiles, namely Brimonidine, Crizotinib, Remdesivir, Vandetanib, and Lapatinib in addition to a chapter discu...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Al-Majed, Abdulrahman A. (Editor)
Format: eBook
Language:English
Published: Amsterdam : Academic Press, 2023.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:"The profiling of drug substances and excipients has become an invaluable tool for the pharmaceutical analyst in his quest for the best quality analytical data. Volume 48 contains five profiles, namely Brimonidine, Crizotinib, Remdesivir, Vandetanib, and Lapatinib in addition to a chapter discussing pharmaceutical-based cosmetic serums. A profile of this series is similar to a full monograph for a drug substance or excipient, including a description of nomenclature, chemical names, proprietary and nonproprietary names, formulas and structures, appearance, and compendia information following a brief introduction. Physical parameters such as UV, IR, MS, NMR, X-ray diffraction, optical rotation, thermal techniques, hygroscopicity, dissociation constants, solubility, and partition coefficients are then discussed. The book includes a comprehensive list of analytical methods, including titrimetric, spectrophotometric, chromatographic, immunoassay, and radioactive labeling techniques. Stability, pharmacokinetics, metabolism, and excretion as well as pharmacology and toxicology are covered briefly."--Preface.
Physical Description:1 online resource (ix, 218 pages)
Bibliography:Includes bibliographical references and index.
ISBN:9780443193835
0443193835