Vitamins and minerals in neurological disorders /

Vitamins and Minerals in Neurological Disorders offers readers a comprehensive reference addressing their relationship to brain health in a wide variety of neurological diseases.

Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Martin, Colin R., Patel, Vinood B., Preedy, Victor R.
Format:	eBook
Language:	English
Published:	[S.l.] : Academic Press, 2023.
Subjects:	Nervous system > Diseases. Nervous system > Diseases > Nutritional aspects. Vitamin therapy. Vitamins in human nutrition. Minerals in human nutrition. Nervous System Diseases Système nerveux > Maladies. Système nerveux > Maladies > Aspect nutritionnel. Vitaminothérapie. Vitamines dans l'alimentation humaine. Minéraux dans l'alimentation humaine. Minerals in human nutrition Nervous system > Diseases Nervous system > Diseases > Nutritional aspects Vitamin therapy Vitamins in human nutrition Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Mg dysmetabolism and prodegenerative BBB alterations
Mg and neuroinflammation-based neurodegeneration
Should Mg be used in the treatment of AD?
Applications to other neurological conditions
Other components of interest
Mini-dictionary of terms
Key facts of Alzheimer's disease (AD)
Key facts of the role of magnesium (Mg) in AD
Summary points
References
Chapter 5: Copper, oxidative stress, Alzheimer's disease, and dementia
Introduction
Why Cu has much to do with Alzheimer's disease
Alzheimer's disease
Alzheimer's disease: General description
Alzheimer's disease diagnosis
Cu intake and regulation in physiology
Cu intake in human diet and drinking water
Cu regulation in physiology
Cu dysregulation in Wilson disease and in Menkes disease
Cu imbalance in Alzheimer's disease
The model of Cu displacement and dysregulation in Alzheimer's disease
The scientific basis for considering CuAD as a subtype of Alzheimer's disease
Implementation of a Cu diet to decrease the CuAD risk
Cu diet in Alzheimer's disease
Requirement for a rapid test for non-Cp Cu assessment
Application to other neurological conditions
Other component of interest: Oxidative stress and Alzheimer's disease
Cu and GSH interplay
Applications to other areas: Cu in type 2 diabetes
Mini-dictionary of terms
Summary points
References
Chapter 6: Chromium and Alzheimer's disease
Introduction
Alzheimer's disease
Characteristic features of AD in terms of brain insulin resistance
Other triggers associated with AD and brain insulin resistance
Chromium
Nutrition and neuroprotection
Neuroscientific aspects
Nutritional aspects
Applications to other neurological conditions
Other components of interest
Mini-dictionary of terms
Key facts of Alzheimer's disease.
Key facts of chromium
Summary points
References
Part II: Amyotrophic lateral sclerosis
Chapter 7: Riboflavin and lower motor neuron diseases
Introduction
Riboflavin transporters deficiencies (RTD)
Pathophysiology of RTD
Clinics of riboflavin transporters deficiencies
Adult-onset RTD and differential diagnoses
Riboflavin and amyotrophic lateral sclerosis (ALS)
ALS clinics
Pathophysiology of ALS
Conclusion
Summary points
References
Part III: Brain injury
Chapter 8: Vitamin C (l-ascorbic acid) in brain injury
Introduction
Vitamin C
Traumatic brain injury
Therapeutic effects of vitamin C
Antiinflammatory and endothelial-stabilizing effects
Therapeutic effects in brain injury
Vitamin C dosing and routes of administration in brain injury
Risks and adverse effects
Conclusions
Applications to other neurological conditions
Other components of interest
Mini-dictionary of terms
Key facts
Summary points
References
Chapter 9: Antioxidants in brain injury with or without antibiotics
Introduction
Epidemiology
Mechanism of TBI propagation
Classification of TBI for targeted therapy
Hospitalization and treatment
Use of antibiotics in TBI
Ceftriaxone
Amoxicillin
Amoxicillin and clavulanic acid or sulbactam
Doxycycline
Minocycline
Reactive oxygen species and antioxidant therapy
Antioxidants used in TBI
Dexamethasone
Methyl prednisolone
Lazaroid
Tirilazad
d-Penicillamine
Melatonin
Tempol
Resveratrol
Hydrazine
Antibiotics in combination with antioxidants
Concluding remarks
Applications to other neurological conditions
Key facts
Summary points
References
Chapter 10: Vitamin D level and the outcome after traumatic brain injury
Introduction
Vitamin D.
Traumatic brain injury and neuroendocrine disturbance
Vitamin D deficiency and androgen synthesis in TBI
Role of vitamin D in neuroprotection
Paucity of vitamin D in association with severity of TBI
Applications to other areas of neurological conditions
Other component of interest
Conclusion
Mini-dictionary terms
Vitamin D
Post traumatic cognitive dysfunction
Post TBI complications
Key facts
Vitamin D deficiency
Vitamin D in TBI
Summary points
References
Chapter 11: Zinc and traumatic brain injury
Introduction
Pathophysiology of TBI
Zinc in physiology
Dietary zinc
Zinc in the brain
Implications of altered zinc homeostasis in TBI
Zinc changes following TBI
Mechanisms of zinc neurotoxicity and neuroprotection
Dietary zinc in TBI
Zinc deficiency in TBI
Zinc supplementation in TBI
The potential for therapeutic approaches that target zinc
Zinc chelation
Zinc chaperones
Conclusion
Applications to other neurological conditions
Other components of interest
Mini dictionary of terms
Key facts of TBI
Key facts of zinc in the brain
Summary points
References
Part IV: Cerebral palsy
Chapter 12: Cerebral palsy: Evaluating vitamin D levels
Introduction
Vitamin D physiology
Role of vitamin D
Cerebral palsy and vitamin D
Conclusion
Applications to other neurological conditions
Other components of interest
Key facts of cerebral palsy (CP): Evaluating vitamin D levels
Dictionary of terms
Summary points
References
Part V: Dietary neurotoxins
Chapter 13: Linking copper and neurotoxic activities to the CNS
Introduction
How do we get copper?
Copper and the diet
Nutritional aspects and disease
Copper absorption and transport
Homeostasis of copper in the brain
Copper and brain metabolism.
Copper and genetic disorder: Wilson's and Menke's disease
Copper and cellular neurodegeneration
Copper and Alzheimer
Copper and association with Parkinson's disease
Copper supplementation
Copper and zinc supplementation
Conclusion
Mini-dictionary of terms
Key facts
Summary points
References
Part VI: Epilepsy
Chapter 14: Vitamin E and neuroprotection in epilepsy
Introduction
The pathogenic triad
Glutamate-mediated excitotoxicity
Neuroinflammation
Oxidative stress
Vitamin E: General characteristics
VE and its effects on the pathogenic triad of epilepsy
Animal studies
Clinical trials
Conclusion
Mini dictionary
Key facts of vitamin E
Summary points
References
Chapter 15: Selenium use in epilepsy
Introduction
Selenium as an antioxidant
Glutathione peroxidase
Thioredoxin reductase
Selenium deficiency
Selenium toxicity
Selenium and neurological disorders
Selenium and epilepsy
Human studies
Selenium as biomarker
Selenium as treatment
Animal studies
Conclusions
Applications to other neurological conditions
Other components of interest
Mini-dictionary of terms
Key facts of selenium
Summary
References
Chapter 16: Correlation of reduced vitamin C and minerals with epilepsy
Introduction
Neuronal distortion in epilepsy
Classification of epileptic seizures
Reduced vitamin C in epilepsy
Reduced minerals in epilepsy
Conclusion
Applications to other neurological conditions
Other components of interest
Mini-dictionary of terms
Key facts of reduced vitamin C and minerals in epilepsy
Summary points
References
Chapter 17: Thiamine, transporters, and epilepsy
Introduction
Chemical structure and biological forms of thiamine
Absorption and transport of thiamine.