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Natural plant products in inflammatory bowel diseases
Natural Plant Products in Inflammatory Bowel Diseases: Preventive and Therapeutic Potential organizes all evidence to understand which natural products are the first steps of investigation and which have strong evidence of their effects in inflammatory bowel diseases, have been tested in clinical trials, and have received approval to be officially used. In addition to providing information regarding the research with natural products in inflammatory bowel diseases, this reference will also highlight the molecular mechanisms behind the effects of natural products in inflammatory bowel diseases with the aid of figures, video animations and dynamic tables. Compiled from research group members from different parts of the world and specialized in inflammatory bowel diseases and related topics, this important reference will be useful to health professionals, researchers, professors, and industry managers as it provides helpful information on the subject, with the potential to inspire health care, relevant research and product innovation. Provides updated information on the pathogenesis of inflammatory bowel diseases and their pharmacological treatments and adverse effects Delivers the most up-to-date information regarding the molecular mechanisms of natural products in inflammatory bowel diseases Organizes the separation of natural products based on their characteristics, including lists of the main results of natural products in experiments conducted in vitro with animals, and in humans with IBDs.
Intro -- Natural Plant Products in Inflammatory Bowel Diseases: Preventive and Therapeutic Potential -- Copyright -- Contents -- Contributors -- Preface -- Chapter 1 Introduction: History of inflammatory bowel diseases and relevance of natural plant products -- 1 . History of inflammatory bowel diseases -- 1.1 Natural plant products -- Acknowledgments -- References -- Chapter 2 Pathogenesis: Crohn's disease and ulcerative colitis -- 1 . Etiology -- 1.1 Genetics -- 1.2 Microbiota -- 1.3 Immune dysfunction -- 1.4 Environmental factors 2 . Clinical, histological, and physiological implications -- 3 . In vitro and animal models -- 3.1 Inflammatory bowel disease animal models -- 3.1.1 Chemically-induced mouse models of inflammatory bowel diseases -- 3.1.2 Genetically-induced mouse models of inflammatory bowel diseases -- 3.1.2.1 Adoptive transfer colitis -- 3.2 In vitro models -- 3.2.1 2-D intestinal cell culture -- 3.2.2 3-D organoid cell culture -- 3.2.3 Microinjection of patient-derived 3-D organoids -- 3.2.4 Apical-out organoids -- 3.2.5 Gut-on-chip -- 4 . Conclusions and future perspectives -- Acknowledgments -- 1 . Introduction -- 2 . Western diet -- 3 . Mediterranean diet -- 4 . Diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols -- 5 . Plant-based diet -- 6 . Paleolithic diet -- 7 . Conclusion -- Acknowledgments -- References -- Chapter 5 Fruits -- 1 . Introduction -- 2 . Fruits on inflammatory bowel diseases -- 2.1 Grape ( Vitis spp.) -- 2.2 Apple ( Malus domestica) -- 2.3 Mango ( Mangifera indica L.) -- 2.4 Berry fruits -- 2.5 Pomegranate ( Punica granatum L.) -- 3 . Concluding remarks -- References -- Chapter 6 Cereal grains and vegetables -- 1 . Introduction -- 2 . Cereal grains -- 2.1 Barley ( Hordeum vulgare) -- 2.2 Corn ( Zea mays) -- 2.3 Oat ( Avena sativa) -- 2.4 Rice ( Oryza sativa) -- 2.5 Soy ( Glycine max) -- 2.6 Wheat ( Triticum aestivum) -- 2.7 Others -- 3 . Vegetables -- 3.1 Pulses -- 3.1.1 Beans ( Phaseolus vulgaris, Canavalia gladiate, Vigna unguiculata) -- 3.1.2 Chickpea ( Cicer arietinum) -- 3.1.3 Lupin ( Lupinus albus) -- 3.1.4 Pea ( Pisum sativum) -- 3.2 Bulbs -- 3.3 Cruciferous -- 3.4 Leafy greens -- 3.4.1 Basil (Ocimum spp.) -- 3.4.2 Purslane (Portulaca oleracea) -- 3.4.3 Others.
edited by Roberto de Paula do Nascimento [and six others].