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Liquid chromatography. Volume 1, Fundamentals and instrumentation.

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Liquid Chromatography: Fundamentals and Instrumentation, Third Edition offers a single source of authoritative information on all aspects of the practice of modern liquid chromatography. The book gives those working in academia and industry the opportunity to learn, refresh, and deepen their underst...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Fanali, Salvatore (Editor), Chankvetadze, Bezhan (Editor), Haddad, Paul R. (Editor), Poole, Colin F. (Editor), Riekkola, Marja (Editor)
Format: eBook
Language:English
Published: Amsterdam : Elsevier, 2023.
Edition:Third edition /
Series:Handbooks in Separation Science Series.
Subjects:
Liquid chromatography.
Chromatographie en phase liquide.
liquid chromatography.
Liquid chromatography
Cromatografia de líquids.
Electronic books.
Llibres electrònics.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Intro
  • Liquid Chromatography: Fundamentals and Instrumentation
  • Copyright
  • Contents
  • Contributors
  • Chapter 1: Milestones in the development of liquid chromatography
  • 1.1. Introduction
  • 1.1.1. Developments before 1960
  • 1.1.2. HPLC at the beginning
  • 1.2. HPLC theory and practice
  • 1.2.1. New HPLC modes and techniques
  • 1.2.2. Selection of conditions for the control of selectivity
  • 1.3. Columns
  • 1.3.1. Particles and column packing
  • 1.3.2. Stationary phases and selectivity
  • 1.4. Equipment
  • 1.5. Detectors
  • Apologies and Acknowledgments
  • References
  • Further reading
  • Chapter 2: Kinetic theories of liquid chromatography
  • 2.1. Introduction
  • 2.2. Macroscopic kinetic theories
  • 2.2.1. Lumped kinetic model
  • 2.2.1.1. The van Deemter plate height equation
  • 2.2.2. General rate model
  • 2.2.2.1. General rate model for monolith columns
  • 2.2.2.2. General rate model for core-shell particles
  • 2.2.2.3. Moment analysis
  • 2.2.3. Lumped pore diffusion model
  • 2.2.4. The equivalence of the macroscopic kinetic models
  • 2.2.5. Kinetic theory of non-linear chromatography
  • 2.3. Microscopic kinetic theories
  • 2.3.1. Stochastic model
  • 3.4.4. Efficiency (N) and plate height (H)
  • 3.4.5. Resolution (Rs)
  • 3.4.6. Peak symmetry
  • 3.4.7. Hydrodynamic parameters-van Deemter equation
  • 3.5. Column testing and evaluation
  • 3.5.1. Engelhardt column test
  • 3.5.2. Tanaka column test
  • 3.5.3. Other column test methods
  • 3.6. Conclusions and perspectives
  • References
  • Chapter 4: General instrumentation in HPLC*
  • 4.1. Introduction
  • 4.2. Instrumental set-up
  • 4.2.1. Mobile-phase/solvent reservoir
  • 4.2.2. Solvent delivery system
  • 4.2.3. Sample introduction device
  • 4.2.4. Pre-column apparatus
  • 4.2.5. Column
  • 4.2.6. Post-column apparatus
  • 4.2.7. Detector(s)
  • 4.2.8. Data collection and output
  • 4.2.9. Post-detection eluent processing
  • 4.2.10. Connective tubing and fittings
  • 4.3. Related HPLC techniques
  • Further reading
  • Chapter 5: Liquid-solid chromatography
  • 5.1. Introduction
  • 5.2. Retention and separation
  • 5.2.1. The retention process (``mechanism)́́
  • 5.2.2. Solute and solvent localization
  • 5.2.3. Selectivity
  • 5.3. Method development
  • 5.3.1. Thin-layer chromatography
  • 5.3.2. Selection of the mobile phase
  • 5.3.3. Example of method development