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Nicotinic acetylcholine receptors in health and disease /

Nicotinic Acetylcholine Receptors in Health and Disease provides the latest information Nicotinic acetylcholine receptors (nAChRs), which are involved in numerous diseases, including Alzheimer's, Parkinson's, and schizophrenia, and are important potential translational targets for treatmen...

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Bibliographic Details
Main Author: Boyd, R. Thomas
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Published: London, UK : Academic Press, 2023.
Subjects:
Nicotinic receptors.
Receptors, Nicotinic
Récepteurs nicotiniques.
Nicotinic receptors
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • 4.2. Nicotine metabolism
  • 4.3. Presentation of nicotine addiction in humans and in animal models
  • 4.4. Reward pathways for nicotine
  • 4.5. Genetic involvement in nicotine addiction
  • 4.6. nAChR subtypes involved in the effects of nicotine on reward and aversion
  • 4.7. Pharmacotherapy for nicotine addiction
  • 4.8. Other potential candidates for smoking cessation
  • References
  • Chapter Five: Disease associations-Alzheimers disease, schizophrenia, Parkinsons disease, autism, and cancer
  • 5.1. Alzheimers disease
  • 5.1.1. Background
  • 5.1.2. Cholinergic role in Alzheimers disease
  • 5.1.3. Amyloid beta
  • 5.1.4. Interactions between amyloid beta and nAChRs
  • 5.1.5. Potential therapies
  • 5.1.6. Summary
  • 5.2. Schizophrenia
  • 5.2.1. Basics of schizophrenia
  • 5.2.2. Cholinergic role in schizophrenia
  • 5.2.3. nAChRs and schizophrenia
  • 5.2.4. Cholinergic drugs for possible schizophrenia treatment
  • 5.2.5. Summary
  • 5.3. Autism
  • 5.3.1. Basics of autism
  • 5.3.2. Evidence for a cholinergic role in ASD
  • 5.3.3. nAChRs and autism
  • 5.3.4. Cholinergic approaches to treating autism
  • 5.3.5. Summary
  • 5.4. Parkinsons disease
  • 5.4.1. Background
  • 5.4.2. Cholinergic role in Parkinsons disease
  • 5.4.3. Treatment using cholinergic modulation
  • 5.4.4. Effects on neurodegeneration
  • 5.4.5. Treatment of LIDs
  • 5.4.6. Improvement in motor symptoms
  • 5.4.7. Summary
  • 5.5. Cancer
  • 5.5.1. Introduction
  • 5.5.2. Nicotinic cholinergic systems and nAChRs are present in normal and cancerous lung and pancreas
  • 5.5.3. Mechanisms of nicotine action in lung and pancreatic cancer
  • 5.5.4. Possible treatment by modulation of cholinergic signaling and nAChRs
  • References
  • Chapter Six: Role of neuronal nAChRs in normal development and plasticity.