Emerging nanotechnologies for medical applications /

Emerging Nanotechnologies for Medical Applications focuses on both commercial and premarket tools and their applications in medicine. The book develops the concept of integrating different technologies along a hierarchical structure of biological systems and clarifies biomechanical interactions on d...

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Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Ahmad, Nabeel, Packirisamy, Gopinath
Format:	eBook
Language:	English
Published:	Amsterdam, Netherlands ; Oxford, United Kingdom ; Cambridge MA : Elsevier, [2023]
Series:	Micro and nano technologies series
Subjects:	Nanomedicine. Nanotechnology. Nanomedicine Nanotechnology Nanomédecine. Nanotechnologie. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Front cover
Half title
Title
Copyright
Contents
Contributors
Chapter 1 Introduction to nanoengineering and nanotechnology for biomedical applications
1.1 Introduction to nanotechnology
1.2 Historical evolution of nanotechnology
1.3 Importance of nanotechnology and nanoengineering
1.4 Fabrication methods in nanotechnology
1.4.1 Top-down approaches
1.4.2 Bottom-up approach
1.5 Physico-chemical characteristics of nanostructures
1.5.1 Size and surface area
1.5.2 Shape and aspect ratio
1.5.3 Surface charges
1.5.4 Surface plasma resonance
1.5.5 Crystalline structure
1.6 Nanomachines, nanodevices, and nanoengineering
1.6.1 Nanomotors
1.6.2 Nanorobots
1.6.3 Nubots
1.6.4 Biochip
1.6.5 Nanoknife
1.7 Application in biomedicine and diagnosis
1.7.1 Target drug delivery
1.7.2 Theranostics
1.7.3 Biosensors
1.7.4 Cancer treatment
1.7.5 Immunotherapy
1.8 Summary
References
Chapter 2 Nanoengineering/technology for tissue engineering and organ printing
2.1 Introduction
2.2 Cells in tissue engineering
2.3 Scaffolds
2.4 Growth factors
2.5 Nanotechnology in three-dimensional (3D) organ printing
2.5.1 Carbon nanomaterials
2.5.2 Ceramic nanoparticle
2.5.3 Nanofibers
2.5.4 Metal nanoparticles
2.6 3D printing methods for tissue engineering
2.6.1 Fused deposition modeling
2.6.2 Stereolithography
2.6.3 Selective laser sintering
2.6.4 Inkjet bioprinting
2.6.5 Laser-assisted bioprinting
2.7 Future direction
References
Chapter 3 Nanoengineering and nanotechnology for diagnosis and treatment of CNS and neurological diseases
3.1 Introduction
3.2 Nano approaches toward CNS drug delivery
3.3 Application of NPs in the treatment of brain diseases and disorders
3.3.1 Brain tumor
3.3.2 Brain infections (BIs).
3.3.3 Traumatic brain injury (TBI)
3.3.4 Ischemic stroke (IS )
3.3.5 Amnesia
3.3.6 Autism spectrum disorder (ASD)
3.3.7 Amyotrophic lateral sclerosis (ALS)
3.3.8 Alzheimer's disease (AD)
3.3.9 Parkinson's disease (PD)
3.3.10 Huntington disease (HD)
3.3.11 Multiple sclerosis (MS)
3.3.12 Epilepsy
3.4 Importance and application of nanotubes in healthcare
3.4.1 Application of carbon nanotubes in central nervous system disorders
3.5 Toxicity of carbon nanotubes in living cells and neural tissue
3.6 Carbon nanotubes with chemically functionalized surfaces for biomedical applications
3.7 Neuroengineering carbon nanotubes in ischemic stroke and other CNS disorders
3.8 Limitations of carbon nanotubes in clinical application and commercialization
3.9 Emerging future potential applications of CNTs
3.10 Conclusion and future prospective
References
Chapter 4 Nanoparticles for diagnosis and treatment of renal diseases
4.1 Introduction
4.2 Current therapies for CKD and their challenges
4.3 Why nanoparticles for kidney diseases?
4.4 Types of nanoparticles used in CKD
4.4.1 Liposomes
4.4.2 Dendrimers
4.4.3 Polymeric nanoparticles
4.4.4 Metal nanoparticles
4.5 Bio-distribution and interaction of nanoparticles
4.6 Applications of nanoparticles for kidney diseases and diagnosis
4.6.1 Drug delivery
4.6.2 Diagnostic applications
4.6.3 Detection of kidney damage through biomarkers using nanoparticles
4.6.4 Research tools
4.7 Targeted drug delivery to kidney tissues
4.7.1 Glomerular targeting
4.7.2 Renal tubules as targeting site
4.7.3 Podocytes targeting
4.8 Nanotechnology-based treatment for kidney diseases
4.8.1 Diabetic kidney disease
4.8.2 Kidney neoplasms
4.8.3 Nanoparticles for ESRD
4.9 Conclusion and future perspectives
References.
Chapter 5 Nanotechnology for diagnosis and treatment of dental and orthopedic diseases
5.1 Nanotechnology and nanomedicine
5.1.1 Introduction
5.1.2 History
5.2 Dentistry
5.2.1 Disease diagnosis and treatment
5.2.2 Other applications
5.3 Orthopedics
5.3.1 Diseases and diagnosis
5.3.2 Other applications
5.4 Limitations of nanotechnology
5.5 Conclusion and prospects
References
Chapter 6 Nanoengineering/technology for diagnosis and treatment of ophthalmic diseases
6.1 Introduction
6.2 Multimodal imaging technology
6.3 Imaging-assisted early diagnosis
6.4 Nanodrug delivery and therapeutics
6.4.1 Nanomaterials
6.4.2 Nanomedicine
6.5 Summary
Acknowledgments
References
Chapter 7 Nanoengineering-based approaches for antimicrobial materials and coatings
7.1 Introduction
7.2 Microbial facet for antimicrobial coatings
7.3 Different strategies for antimicrobial coatings
7.3.1 Repellant coating
7.3.2 Contact killing coating
7.3.3 Release-based coatings
7.3.4 Stimuli^^e2^^80^^93responsive coatings
7.4 Mechanism of action of nanoparticles
7.5 Nanoparticles in eradicating microbes
7.5.1 Metallic nanoparticles
7.5.2 Metal oxide nanoparticles
7.5.3 Polymeric nanoparticles
7.6 Commercial status of antimicrobial coatings
7.7 Prospect and challenges of nanomaterials for antimicrobial coatings
References
Chapter 8 Wearable technology in healthcare engineering
8.1 Introduction
8.2 Literature survey
8.2.1 Wearable technology for physical activity monitoring
8.2.2 Wearable technology for mental health monitoring
8.2.3 Wearable technology for diabetes monitoring
8.2.4 Wearable technology for sleep monitoring
8.2.5 Wearable technology for respiratory measurement
8.3 Wearables-based on various mechanisms.
8.3.1 Optics-based wearable devices
8.3.2 Colorimetric-based wearable devices
8.3.3 Electrochemical-based wearable devices
8.4 Potential materials for wearable devices
8.4.1 Hydrogels
8.4.2 Liquid conductors
8.4.3 Polymers
8.4.4 Nanomaterials
8.5 Integration of big data and AI (Artificial Intelligence) techniques
8.6 Challenges and issues involved
8.6.1 Battery life
8.6.2 Ergonomics
8.6.3 Sealing
8.6.4 Miniaturization and integration
8.6.5 Safety, security, and privacy
8.7 Future aspects
References
Chapter 9 Nanotechnology for point-of-care (POC) diagnostics
9.1 Introduction
9.1.1 Carbon-based nanomaterials interesting characteristics for point-of-care diagnostics
9.1.2 Noncarbon-based nanomaterials interesting characteristics for point-of-care diagnostics
9.2 Point-of-diagnostics using nanomaterials
9.2.1 0D nanomaterials
9.2.2 1D nanomaterials
9.2.3 2D nanomaterials
9.2.4 3D nanomaterials
9.3 Main POC diagnostics technologies using nanomaterials
9.3.1 Lateral flow strips
9.3.2 Printable electrochemical biosensors
9.3.3 Precise fluid control containing devices
9.4 Main challenges of nano-based POC diagnostics
9.5 Conclusion
References
Chapter 10 Nanotechnology-based healthcare engineering products and recent patents-an update
10.1 Introduction
10.2 Nanotechnology-based healthcare products in the market currently
NanoFUSE bioactive matrix
10.3 Applications of nanotechnology
10.4 List of recent patents in tabulated form Table 10.4
10.5 Current challenges (toxicity and safety &amp
risk management) confronted by nanotechnology for implementation in healthcare
10.6 Future scope and conclusion
References
Chapter 11 Nanoinformatics and nanomodeling: Recent developments in computational nanodrug design and delivery systems.
11.1 Introduction
11.2 Models used in the nanodrug designing
11.2.1 Continuum modeling
11.2.2 Molecular modeling
11.2.3 Stochastic modeling
11.3 Nanoinformatics in modern drug discovery and delivery
11.3.1 Software, databases, and hardware infrastructure for nanoinformatics
11.3.2 Forums: implementation &amp
maintenance
11.3.3 Collaboration &amp
related network associations
11.4 Disease and nanodrug targeting, modeling, and delivery
11.4.1 Concept of disease/cancer and protein targets
11.5 Approaches toward drug targeting
11.5.1 Traditional approach to drug targeting
11.5.2 Nanodrug targeting advantages over traditional approaches
11.5.3 Computational approaches
11.6 Precise role of nanoinformatics in personalized cancer therapy
11.6.1 Artificial intelligence and machine learning in nanoinformatics and personalized medicine
11.7 The science of small things taking over AIM world
11.8 Current initiatives and projects for computational nanodrug design and delivery
11.9 Promises, bottleneck, and future challenges
11.10 Conclusion
References
Index
Back cover.