http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Emerging nanotechnologies for medical applications
Emerging Nanotechnologies for Medical Applications focuses on both commercial and premarket tools and their applications in medicine. The book develops the concept of integrating different technologies along a hierarchical structure of biological systems and clarifies biomechanical interactions on different levels for the analysis of multiscale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it demonstrates how knowledge can be utilized in a range of areas, including the diagnosis and treatment of various human diseases, and in alternative energy production. This book is an important reference source for scientists and researchers involved in micro- and nano-engineering, bio-nanotechnology, biomedical engineering, nanomedicine, and industries involved with optical devices, computer simulation and pharmaceuticals.
Front cover -- Half title -- Title -- Copyright -- Contents -- Contributors -- Chapter 1 Introduction to nanoengineering and nanotechnology for biomedical applications -- 1.1 Introduction to nanotechnology -- 1.2 Historical evolution of nanotechnology -- 1.3 Importance of nanotechnology and nanoengineering -- 1.4 Fabrication methods in nanotechnology -- 1.4.1 Top-down approaches -- 1.4.2 Bottom-up approach -- 1.5 Physico-chemical characteristics of nanostructures -- 1.5.1 Size and surface area -- 1.5.2 Shape and aspect ratio -- 1.5.3 Surface charges -- 1.5.4 Surface plasma resonance -- 1.5.5 Crystalline structure -- 1.6 Nanomachines, nanodevices, and nanoengineering -- 1.6.1 Nanomotors -- 1.6.2 Nanorobots -- 1.6.3 Nubots -- 1.6.4 Biochip -- 1.6.5 Nanoknife -- 1.7 Application in biomedicine and diagnosis -- 1.7.1 Target drug delivery -- 1.7.2 Theranostics -- 1.7.3 Biosensors -- 1.7.4 Cancer treatment -- 1.7.5 Immunotherapy -- 1.8 Summary -- References -- Chapter 2 Nanoengineering/technology for tissue engineering and organ printing -- 2.1 Introduction -- 2.2 Cells in tissue engineering -- 2.3 Scaffolds -- 2.4 Growth factors -- 2.5 Nanotechnology in three-dimensional (3D) organ printing -- 2.5.1 Carbon nanomaterials -- 2.5.2 Ceramic nanoparticle -- 2.5.3 Nanofibers -- 2.5.4 Metal nanoparticles -- 2.6 3D printing methods for tissue engineering -- 2.6.1 Fused deposition modeling -- 2.6.2 Stereolithography -- 2.6.3 Selective laser sintering -- 2.6.4 Inkjet bioprinting -- 2.6.5 Laser-assisted bioprinting -- 2.7 Future direction -- References -- Chapter 3 Nanoengineering and nanotechnology for diagnosis and treatment of CNS and neurological diseases -- 3.1 Introduction -- 3.2 Nano approaches toward CNS drug delivery -- 3.3 Application of NPs in the treatment of brain diseases and disorders -- 3.3.1 Brain tumor -- 3.3.2 Brain infections (BIs).
3.3.3 Traumatic brain injury (TBI) -- 3.3.4 Ischemic stroke (IS ) -- 3.3.5 Amnesia -- 3.3.6 Autism spectrum disorder (ASD) -- 3.3.7 Amyotrophic lateral sclerosis (ALS) -- 3.3.8 Alzheimer's disease (AD) -- 3.3.9 Parkinson's disease (PD) -- 3.3.10 Huntington disease (HD) -- 3.3.11 Multiple sclerosis (MS) -- 3.3.12 Epilepsy -- 3.4 Importance and application of nanotubes in healthcare -- 3.4.1 Application of carbon nanotubes in central nervous system disorders -- 3.5 Toxicity of carbon nanotubes in living cells and neural tissue -- 3.6 Carbon nanotubes with chemically functionalized surfaces for biomedical applications -- 3.7 Neuroengineering carbon nanotubes in ischemic stroke and other CNS disorders -- 3.8 Limitations of carbon nanotubes in clinical application and commercialization -- 3.9 Emerging future potential applications of CNTs -- 3.10 Conclusion and future prospective -- References -- Chapter 4 Nanoparticles for diagnosis and treatment of renal diseases -- 4.1 Introduction -- 4.2 Current therapies for CKD and their challenges -- 4.3 Why nanoparticles for kidney diseases? -- 4.4 Types of nanoparticles used in CKD -- 4.4.1 Liposomes -- 4.4.2 Dendrimers -- 4.4.3 Polymeric nanoparticles -- 4.4.4 Metal nanoparticles -- 4.5 Bio-distribution and interaction of nanoparticles -- 4.6 Applications of nanoparticles for kidney diseases and diagnosis -- 4.6.1 Drug delivery -- 4.6.2 Diagnostic applications -- 4.6.3 Detection of kidney damage through biomarkers using nanoparticles -- 4.6.4 Research tools -- 4.7 Targeted drug delivery to kidney tissues -- 4.7.1 Glomerular targeting -- 4.7.2 Renal tubules as targeting site -- 4.7.3 Podocytes targeting -- 4.8 Nanotechnology-based treatment for kidney diseases -- 4.8.1 Diabetic kidney disease -- 4.8.2 Kidney neoplasms -- 4.8.3 Nanoparticles for ESRD -- 4.9 Conclusion and future perspectives -- References.
Chapter 5 Nanotechnology for diagnosis and treatment of dental and orthopedic diseases -- 5.1 Nanotechnology and nanomedicine -- 5.1.1 Introduction -- 5.1.2 History -- 5.2 Dentistry -- 5.2.1 Disease diagnosis and treatment -- 5.2.2 Other applications -- 5.3 Orthopedics -- 5.3.1 Diseases and diagnosis -- 5.3.2 Other applications -- 5.4 Limitations of nanotechnology -- 5.5 Conclusion and prospects -- References -- Chapter 6 Nanoengineering/technology for diagnosis and treatment of ophthalmic diseases -- 6.1 Introduction -- 6.2 Multimodal imaging technology -- 6.3 Imaging-assisted early diagnosis -- 6.4 Nanodrug delivery and therapeutics -- 6.4.1 Nanomaterials -- 6.4.2 Nanomedicine -- 6.5 Summary -- Acknowledgments -- References -- Chapter 7 Nanoengineering-based approaches for antimicrobial materials and coatings -- 7.1 Introduction -- 7.2 Microbial facet for antimicrobial coatings -- 7.3 Different strategies for antimicrobial coatings -- 7.3.1 Repellant coating -- 7.3.2 Contact killing coating -- 7.3.3 Release-based coatings -- 7.3.4 Stimuli^^e2^^80^^93responsive coatings -- 7.4 Mechanism of action of nanoparticles -- 7.5 Nanoparticles in eradicating microbes -- 7.5.1 Metallic nanoparticles -- 7.5.2 Metal oxide nanoparticles -- 7.5.3 Polymeric nanoparticles -- 7.6 Commercial status of antimicrobial coatings -- 7.7 Prospect and challenges of nanomaterials for antimicrobial coatings -- References -- Chapter 8 Wearable technology in healthcare engineering -- 8.1 Introduction -- 8.2 Literature survey -- 8.2.1 Wearable technology for physical activity monitoring -- 8.2.2 Wearable technology for mental health monitoring -- 8.2.3 Wearable technology for diabetes monitoring -- 8.2.4 Wearable technology for sleep monitoring -- 8.2.5 Wearable technology for respiratory measurement -- 8.3 Wearables-based on various mechanisms.
8.3.1 Optics-based wearable devices -- 8.3.2 Colorimetric-based wearable devices -- 8.3.3 Electrochemical-based wearable devices -- 8.4 Potential materials for wearable devices -- 8.4.1 Hydrogels -- 8.4.2 Liquid conductors -- 8.4.3 Polymers -- 8.4.4 Nanomaterials -- 8.5 Integration of big data and AI (Artificial Intelligence) techniques -- 8.6 Challenges and issues involved -- 8.6.1 Battery life -- 8.6.2 Ergonomics -- 8.6.3 Sealing -- 8.6.4 Miniaturization and integration -- 8.6.5 Safety, security, and privacy -- 8.7 Future aspects -- References -- Chapter 9 Nanotechnology for point-of-care (POC) diagnostics -- 9.1 Introduction -- 9.1.1 Carbon-based nanomaterials interesting characteristics for point-of-care diagnostics -- 9.1.2 Noncarbon-based nanomaterials interesting characteristics for point-of-care diagnostics -- 9.2 Point-of-diagnostics using nanomaterials -- 9.2.1 0D nanomaterials -- 9.2.2 1D nanomaterials -- 9.2.3 2D nanomaterials -- 9.2.4 3D nanomaterials -- 9.3 Main POC diagnostics technologies using nanomaterials -- 9.3.1 Lateral flow strips -- 9.3.2 Printable electrochemical biosensors -- 9.3.3 Precise fluid control containing devices -- 9.4 Main challenges of nano-based POC diagnostics -- 9.5 Conclusion -- References -- Chapter 10 Nanotechnology-based healthcare engineering products and recent patents-an update -- 10.1 Introduction -- 10.2 Nanotechnology-based healthcare products in the market currently -- NanoFUSE bioactive matrix -- 10.3 Applications of nanotechnology -- 10.4 List of recent patents in tabulated form Table 10.4 -- 10.5 Current challenges (toxicity and safety &amp -- risk management) confronted by nanotechnology for implementation in healthcare -- 10.6 Future scope and conclusion -- References -- Chapter 11 Nanoinformatics and nanomodeling: Recent developments in computational nanodrug design and delivery systems.
11.1 Introduction -- 11.2 Models used in the nanodrug designing -- 11.2.1 Continuum modeling -- 11.2.2 Molecular modeling -- 11.2.3 Stochastic modeling -- 11.3 Nanoinformatics in modern drug discovery and delivery -- 11.3.1 Software, databases, and hardware infrastructure for nanoinformatics -- 11.3.2 Forums: implementation &amp -- maintenance -- 11.3.3 Collaboration &amp -- related network associations -- 11.4 Disease and nanodrug targeting, modeling, and delivery -- 11.4.1 Concept of disease/cancer and protein targets -- 11.5 Approaches toward drug targeting -- 11.5.1 Traditional approach to drug targeting -- 11.5.2 Nanodrug targeting advantages over traditional approaches -- 11.5.3 Computational approaches -- 11.6 Precise role of nanoinformatics in personalized cancer therapy -- 11.6.1 Artificial intelligence and machine learning in nanoinformatics and personalized medicine -- 11.7 The science of small things taking over AIM world -- 11.8 Current initiatives and projects for computational nanodrug design and delivery -- 11.9 Promises, bottleneck, and future challenges -- 11.10 Conclusion -- References -- Index -- Back cover.
edited by Nabeel Ahmad, Gopinath Packirisamy.