Forensic genetic approaches for identification of human skeletal remains : challenges, best practices, and emerging technologies /
"Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies provides best practices on processing bone samples for DNA testing. The book outlines forensic genetics tools that are available for the identification of skeletal re...
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| Format: | eBook |
| Language: | English |
| Published: |
Amsterdam :
Academic Press,
[2023]
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | "Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies provides best practices on processing bone samples for DNA testing. The book outlines forensic genetics tools that are available for the identification of skeletal remains in contemporary casework and historical/archaeological investigations. Although the book focuses primarily on the use of DNA for direct identification or kinship analyses, it also highlights complementary disciplines often used in concert with genetic data to make positive identifications, such as forensic anthropology, forensic odontology, and forensic art/sculpting. Unidentified human remains are often associated with tragic events, such as fires, terrorist attacks, natural disasters, war conflicts, genocide, airline crashes, homicide, and human rights violations under oppressive totalitarian regimes. In these situations, extensive damage to soft tissues often precludes the use of such biological samples in the identification process. In contrast, bone material is the most resilient, viable sample type for DNA testing. DNA recovered from bone often is degraded and in low quantities due to the effects of human decomposition, environmental exposure, and the passage of time. The complexities of bone microstructure and its rigid nature make skeletal remains one of the most challenging sample types for DNA testing."--Provided by publisher. |
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| Item Description: | Missing persons and unidentified human remains : yhe world's silent mass disaster / Angie Ambers -- Challenges in forensic genetic investigations of decomposed or skeletonized human remains : environmental exposure, DNA degradation, inhibitors, and low copy number (LCN). Guidelines and best practices for handling and processing human skeletal remains for genetic studies / Angie Ambers -- Facilities design and workflow considerations for processing unidentified human skeletal remains / Odile Loreille -- Location, recovery, and excavation of human remains for forensic testing / Murray K. Marks and Darinka Mileusnic-Polchan -- Skeletal microstructure, bone diagenesis, optimal sample selection, and pre-processing preparation techniques for DNA testing / Angie Ambers -- DNA extraction methods for human skeletal remains / Angie Ambers -- Quantitative and qualitative assessment of DNA recovered from human skeletal remains / Jodie Ward -- Types of DNA markers and applications for identification. Autosomal short tandem repeat (STR) profiling of human skeletal remains / Jeremy Watherson -- Y-chromosome analysis for unidentified human remains (UHR) investigations / Angie Ambers -- Mitochondrial DNA and its use in the forensic analysis of skeletal material / Brandon Letts -- X-chromosome short tandem repeats (X-STRs) : applications for human remains identification / Vivek Sahajpal -- Single nucleotide polymorphisms (SNPs) : ancestry-, phenotype-, and identity-informative SNPs -- Diallelic markers : INDELs and INNULs -- Traditional platforms, alternative strategies, and emerging technologies for DNA analysis of human skeletal remains. Genotyping and sequencing of DNA recovered from human skeletal remains using capillary electrophoresis (CE) / Jodie Ward, Jeremy Watherston, Irene Kahline, Timothy P. McMahon, and Suni M. Edson -- Rapid DNA identification of human skeletal remains / Rosemary Turingan Witkowski, Ranjana Grover, Eugene Tan, and Richard F. Selden -- Emerging technologies for DNA analysis of challenged samples / Nicole Novroski -- Analysis of genetic data recovered from skeletonized human remains. Best practices in the development and effective use of a forensic DNA database for identification of missing persons and unidentified human remains /Michael Hennessey -- Software and database functionality for direct identification and kinshi analysis : the Mass Fatality Identification System (M-FISys) / Howard D. Cash -- Bioinformatic tools for interrogating DNA recovered from human skeletal remains / Frank R. Wendt -- The emerging discipline of forensic genetic genealogy / Colleen Fitzpatrick -- Complementary and multidisciplinary approaches to assist in identification of unidentified human skeletal remains. Forensic anthropology in a DNA world : how anthropological methods complement DNA-based identification of human remains / Eric J. Bartelink -- Generation of a personal chemical profile from skeletonized human remains / Suni M. Edson -- Forensic odontology : historical perspectives and current applications for identification of human remains / Thomas J. David and James M. Lewis -- Forensic facial reconstruction of skeletonized and highly decomposed human remains / Stephen Missal. |
| Physical Description: | 1 online resource (xlii, 584 pages) : illustrations (chiefly color), 1 color map |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9780128163696 0128163690 |