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Plant polysaccharides as pharmaceutical excipients /

Plant Polysaccharides as Pharmaceutical Excipients explores innovative techniques and applications of plant-derived polysaccharides as pharmaceutical excipients. Plant polysaccharides are sustainable, renewable and abundantly available, offering attractive properties in terms of water solubility, sw...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Nayak, Amit Kumar, 1979- (Editor), Hasnain, Md Saquib, 1984- (Editor), Pal, Dilipkumar, 1971- (Editor)
Format: eBook
Language:English
Published: Amsterdam, Netherlands ; Oxford, United Kingdom ; Cambridge MA : Elsevier, [2023]
Subjects:
Excipients.
Polysaccharides > Therapeutic use.
Excipients
Polysaccharides > therapeutic use
Polysaccharides > Emploi en thérapeutique.
Polisacàrids.
Electronic books.
Llibres electrònics.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Plant Polysaccharides as Pharmaceutical Excipients
  • Copyright Page
  • Contents
  • List of contributors
  • Preface
  • 1 Plant polysaccharides: sources, classifications, and extraction methods
  • 1.1 Introduction
  • 1.2 Classification of plant polysaccharides based on their sources
  • 1.2.1 Plant gums
  • 1.2.1.1 Classification of plant gums
  • 1.2.1.2 Advantages of plant gums for pharmaceutical uses
  • 1.2.1.2.1 Biodegradability
  • 1.2.1.2.2 Biocompatibility
  • 1.2.1.2.3 Environmental-friendly processing
  • 1.2.1.2.4 Local availability
  • 1.2.1.3 Disadvantages of plant gums for pharmaceutical uses
  • 1.2.1.3.1 Microbial contamination
  • 1.2.1.3.2 Batch to batch variation
  • 1.2.1.3.3 Uncontrolled rate of hydration
  • 1.2.1.3.4 Reduced viscosity on storage
  • 1.2.2 Plant mucilages
  • 1.2.3 Plant starches
  • 1.3 The extraction of polysaccharides from plant sources
  • 1.3.1 Hot water extraction method
  • 1.3.2 Dilute alkali extraction method
  • 1.3.3 Enzyme-assisted extraction method
  • 1.3.4 Microwave-assisted extraction method
  • 1.3.5 Ultrasonic extraction method
  • 1.3.6 Subcritical water extraction method
  • 1.3.7 Ultrahigh-pressure extraction method
  • 1.3.8 Decompression/vacuum extraction method
  • 1.3.9 Combined extraction method
  • 1.4 Conclusion
  • References
  • 2 Properties of plant polysaccharides used as pharmaceutical excipients
  • Abbreviations
  • 2.1 Introduction
  • 2.2 Sources
  • 2.3 Plant natural sources
  • 2.4 Gum and mucilages
  • 2.4.1 Gum arabica/gum acacia
  • 2.4.2 Albizia gum
  • 2.4.3 Guar gum
  • 2.4.4 Locust bean gum
  • 2.4.5 Honey locust gum
  • 2.4.6 Gum copal
  • 2.4.7 Grevillea robusta gum
  • 2.4.8 Aloe mucilage
  • 2.4.9 Moringa oleifera gum
  • 2.4.10 Phoenix mucilage
  • 2.4.11 Hibiscus mucilage
  • 2.4.12 Cassia tora mucilage
  • 2.4.13 Delonix regia gum
  • 2.4.14 Beal fruit
  • 2.4.15 Psyllium
  • 2.4.16 Okara.
  • 2.4.17 Neem gum
  • 2.4.18 Cashew gum
  • 2.4.19 Olibanum gum
  • 2.4.20 Mango gum
  • 2.4.21 Grewia gum
  • 2.4.22 Moi gum
  • 2.4.23 Tamarind seed polysaccharide
  • 2.5 Cellulose
  • 2.5.1 Microcrystalline cellulose
  • 2.5.2 Cellulose ether derivatives
  • 2.5.3 Cellulose Ester Derivatives
  • 2.6 Starch
  • 2.6.1 Roots and tubers
  • 2.6.2 Yams
  • 2.6.3 Sweet potato
  • 2.6.4 Zingiber officinale (ginger)
  • 2.6.5 Grains and cereals
  • 2.6.5.1 Digitaria genus (Fonio)
  • 2.6.5.2 Pigeon pea
  • 2.6.6 Fruits
  • 2.6.6.1 Plantain starch
  • 2.6.6.2 Breadfruit
  • 2.7 Conclusion
  • References
  • 3 Natural products as pharmaceutical additives in drug delivery systems
  • 3.1 Introduction
  • 3.2 Sources of natural polysaccharide excipients
  • 3.3 Classification of pharmaceutical excipients
  • 3.3.1 Natural polysaccharides as solvents
  • 3.3.2 Natural polysaccharides as thickening agent/viscosity enhancers
  • 3.3.3 Natural polysaccharides as suspending agents/suspenders
  • 3.3.4 Natural polysaccharides as emulsifying agents
  • 3.3.5 Natural polysaccharides as chelating agents
  • 3.3.6 Natural polysaccharides as surface-active agents
  • 3.3.7 Natural polysaccharides as suppository bases
  • 3.3.8 Natural polysaccharides as gelling/semisolid bases
  • 3.3.9 Natural polysaccharides as binders, diluents or fillers
  • 3.3.10 Natural polysaccharides as disintegrants
  • 3.3.11 Natural polysaccharides as coating agent
  • 3.3.12 Natural polysaccharides as Flavor enhancer
  • 3.3.13 Natural polysaccharides as sweetening agents
  • 3.3.14 Natural polysaccharides as preservatives
  • 3.3.15 Polysaccharides used in novel drug delivery systems
  • 3.3.16 Polysaccharides used in nanoparticles drug delivery
  • 3.4 Conclusion
  • Acknowledgments
  • Conflict of interest
  • Author contributions
  • References
  • 4 Plant polysaccharides in pharmaceutical tablets
  • 4.1 Introduction.
  • 7.4.1 Calcium-linked albumin-loaded pectin HDG as colon targeted drug delivery system
  • 7.4.2 Porous and nonporous pectin-based HDGs as tetracycline drug delivery system
  • 7.4.3 Doxorubicin-loaded zein nanoparticle embedded pectin HDG as drug delivery system
  • 7.4.4 Poly(3-methoxydiphenylamine)-pectin HDG as controlled drug delivery system
  • 7.4.5 Soy protein isolate-sugar beet pectin intra-penetrating network HDG as probiotic carrier
  • 7.5 Pharmaceutical applications of gum (Acacia/Arabic/Ghatti/Karaya/Tragacanth/Locust bean/Sterculia)-derived HDG
  • 7.5.1 Gum acacia-zinc oxide nanoparticle HDG with antimicrobial activity
  • 7.5.2 Ag Nanoparticle-loaded poly vinyl alcohol-gum acacia HDG as antibacterial agent
  • 7.5.3 Wound healing property of gum acacia-based HDG
  • 7.5.4 Sodium alginate-gum Arabic HDG as wound healer
  • 7.5.5 Gum Arabic-linked poly vinyl alcohol HDG as folic acid delivery system
  • 7.5.6 5-Flurouracil embedded gum ghatti HDG as anticancer drug delivery system
  • 7.5.7 Etherified gum ghatti as ropinirole HCl oral drug delivery system
  • 7.5.8 Gum karaya-starch crosslinked HDG as drug delivery system
  • 7.5.9 Locust bean tailored HDG as glipizide delivery system
  • 7.5.10 Locust bean-kappa carrageenan HDG as dual drug delivery system
  • 7.5.11 Alginate-Sterculia-based HDG as brain-targeted delivery system
  • 7.5.12 Tragacanth HDG as controlled drug delivery system
  • 7.5.13 Silver-tragacanth HDG as antibacterial drug delivery system
  • 7.5.14 Tragacanth HDG as oral drug delivery of insulin
  • 7.5.15 Tragacanth gum embedded with itaconic acid as an ampicillin controlled delivery system
  • 7.6 Conclusion
  • References
  • 8 Plant polysaccharides-based multiple-units for oral drug delivery
  • 8.1 Introduction
  • 8.2 Advantages of multiple-unit oral drug delivery systems.