Practical application of supercritical fluid chromatography for pharmaceutical research and development /

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable "go-to" reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and indu...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Hicks, Michael B. (Editor), Ferguson, Paul D. (Editor)
Format: eBook
Language:English
Published: London, United Kingdom ; San Diego, CA : Academic Press, 2022.
Series:Separation science and technology (San Diego, Calif.) ; v. 14.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • 1. Application space for SFC in pharmaceutical drug discovery and development<br>2. Evolution and history of SFC as greener preparative Tool<br>3. SFC for chiral resolution of pharmaceuticals<br>4. Advantages of new column technologies with SFC<br>5. Synthetic and process chemistry reaction screening<br>6. Method development approaches for small molecule analytes<br>7. Expanding the boundaries of SFC: starting materials, excipients, lipidated peptide conjugates, PEGs<br>8. Application driven detection<br>9. Advantages of SFC
  • over historical and compendial normal phase methods<br>10. Peptides, proteins and the use of water with SFC methods<br>11. Other miscellaneous applications of SFC as a sustainable analytical tool, nucleic acids and sugars