Biomedical applications of inorganic photochemistry /

Biomedical Applications of Inorganic Photochemistry, Volume 80 in the Advances in Inorganic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Ford, Peter C., Eldik, Rudi van
Format: eBook
Language:English
Published: [S.l.] : Academic Press, 2022.
Series:Advances in inorganic chemistry ; v. 80.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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505 0 |a Intro -- Biomedical Applications of Inorganic Photochemistry -- Copyright -- Contents -- Contributors -- Preface -- Chapter One: Leveraging the photophysical properties of rhenium(I) tricarbonyl complexes for biomedical applications -- 1. Introduction -- 2. Properties and applications of Re(CO)3 complexes -- 3. Re(CO)3 complexes as photoluminescent imaging agents -- 4. Simple diimine Re(CO)3 complexes exhibit anticancer activity -- 5. Pyridylimine Re(CO)3 complexes -- 6. Isonitrile-containing Re(CO)3 complexes -- 7. Photoactivation of Re(CO)3 anticancer agents 
505 8 |a 8. Conclusions and future outlook -- Acknowledgments -- References -- Chapter Two: Strategic design of photofunctional transition metal complexes for cancer diagnosis and therapy -- 1. Introduction -- 2. Transition metal complexes for targeted cancer diagnosis and therapy -- 2.1. Glucose transporters -- 2.2. Biotin receptors -- 2.3. Integrins -- 2.4. G-Protein-coupled receptors -- 2.5. Epidermal growth factor receptor -- 2.6. Carbonic anhydrase -- 2.7. Cyclooxygenase -- 2.8. Sialylated glycoproteins and glycolipids -- 3. Activatable transition metal complexes for cancer diagnosis and therapy 
505 8 |a 3.1. Hypoxia -- 3.2. pH -- 3.3. Polarity -- 3.4. Viscosity -- 3.5. Redox status -- 3.6. Enzymes -- 3.7. Mismatched DNA molecules -- 3.8. Bioorthogonal chemical reporters -- 4. Conclusions and future perspective -- Acknowledgments -- References -- Chapter Three: Advances in the design of photoactivated platinum anticancer complexes -- 1. Introduction -- 2. Discovery of photoactive Pt(IV) anticancer complexes -- 3. Mechanism of action -- 3.1. Radical and ROS generation -- 3.2. DNA as a target -- 3.3. Peptide and protein targets -- 3.4. Induction of immunogenic cell death 
505 8 |a 4. Axial derivatives of Pt(IV) complexes -- 4.1. Targeting vectors -- 4.2. Multi-action derivatives -- 5. Pt(IV) azide-acetylene derivatives via ``click ́́reactions -- 6. Nanocarriers -- 6.1. Proteins -- 6.2. Polysaccharides -- 6.3. Hydrogels -- 6.4. Block copolymers -- 6.5. Polymetallodrugs -- 6.6. Carbon dots -- 6.7. Up-converting nanoparticles (UCNPs) -- 6.8. Summary and prospects -- Acknowledgments -- References -- Chapter Four: Adventures in the photo-uncaging of small molecule bioregulators -- 1. Introduction -- 2. PhotoNORMs and PhotoCORMs -- 2.1. Uncaging nitric oxide 
505 8 |a 2.2. Uncaging carbon monoxide -- 3. Enhancing photoreaction SMB release rates with antennas -- 3.1. Organic chromophore antennas -- 3.2. Semiconductor quantum dot antennas -- 4. Moving toward the phototherapeutic window -- 4.1. Single photon excitation strategies -- 4.2. Simultaneous two photon excitation -- 4.3. Upconverting nanoparticles -- 4.4. Nano-carriers -- 5. Biological targeting -- 5.1. Liposomes -- 5.2. Hollow gold nanoshells -- 5.3. Macrophage Trojan Horses -- 6. Summary -- Acknowledgments -- References 
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