Aptamers engineered nanocarriers for cancer therapy /
Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems pertaining to the manufacture of nano-aptame...
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| Format: | eBook |
| Language: | English |
| Published: |
Cambridge, MA :
Woodhead Publishing,
[2023]
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| Series: | Woodhead Publishing series in biomaterials.
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| Online Access: | Connect to the full text of this electronic book |
| Summary: | Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems pertaining to the manufacture of nano-aptamers - such as toxicity, thermal stability, cost efficiency, tumor penetration and blood stability. Key chapters cover cell-SELEX technology for aptamer selection, mechanisms of multi-drug resistance of cancer, the relevance of aptamers as anticancer therapies, as well as the broad range of aptamer-functionalized nanostructures available. This book provides exciting insights into this relatively new approach to cancer therapeutics, and will be of interest to materials scientists, biomedical engineers, molecular biologists, biochemists and clinical scientists, with a focus on cancer therapy. |
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| Item Description: | 1. Cell-SELEX technology for aptamer selection<br>2. Biological characteristics of aptamers<br>3. Mechanisms of multi-drug resistance of cancer<br>4. Relevance of aptamers as targeting ligands for anticancer therapies<br>5. Aptamers as smart ligands for nano-carriers cancer targeting<br>6. Aptamer-functionalized liposomes for targeted cancer therapy<br>7. Aptamer-functionalized micelles for targeted cancer therapy<br>8. Aptamer-functionalized nanoparticles for targeted cancer therapy<br>9. Aptamer-functionalized PLGA nanoparticles for targeted cancer therapy<br>10. Aptamer-functionalized silica nanoparticles for targeted cancer therapy<br>11. Aptamer-functionalized gold nanoparticles for targeted cancer therapy<br>12. Aptamer-functionalized dendrimers for targeted cancer therapy<br>13. Aptamer-functionalized carbon nanotubes for targeted cancer therapy<br>14. Aptamer-functionalized quantum dots for targeted cancer therapy<br>15. Cancer immunotherapy via nucleic acid aptamers<br>16. Aptamer-based imaging and diagnostics for cancer cells<br>17. Microdevice-based aptamer sensors<br>18. Aptamer-based microfluidics for circulating tumor cells<br>19. Aptamer-based theranostic approaches for treatment of cancer<br>20. Challenges of aptamers as targeting ligands for anticancer therapies<br>21. Clinical use and future perspective of aptamers |
| Physical Description: | 1 online resource : illustrations (black and white, and colour). |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 0323855768 9780323855761 0323858813 9780323858816 |