Macrophages in the human body : a tissue level approach /

"Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic popu...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Saraiva Camara, Niels Olsen, Braga, Tárcio Teodoro
Format: eBook
Language:English
Published: London, UK : Academic Press, 2022.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:"Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions."--
Item Description:Includes index.
Physical Description:1 online resource
ISBN:9780128213865
0128213868