Unraveling the complexities of metastasis : transition from a segmented view to a conceptual continuum /
"Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognosti...
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| Other Authors: | , , |
| Format: | eBook |
| Language: | English |
| Published: |
London, UK :
Academic Press,
2022.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- 2
- Multiple roles of circulating tumor cells and exosomes in cancer metastasis: implications for therapeutic inter ...
- Introduction
- CTCs involvement in metastatic progression
- Strategies for isolation and enrichment of CTCs
- Characterization of CTCs
- Exosomes involvement in metastatic progression
- Strategies for detection, isolation, and enrichment of exosomes
- Characterization of exosomes
- Clinical impact of CTCs and exosomes
- Conclusions and future perspectives
- References
- 3
- Diagnosis and treatment of metastatic prostate cancer: the role of imaging, liquid biopsies, and biomarkers for ...
- Introduction
- Overview of prostate cancer disease states and treatment options
- Proliferative inflammatory atrophy
- Localized prostate cancer and treatment options
- Metastatic castration-resistant prostate cancer and treatment options
- Improved imaging and image-guided biopsy for prostate cancer
- Imaging signatures of hypoxia
- Gene signature panels for prostate cancer risk stratification
- Next-generation sequencing and prostate cancer: cell-free nucleic acids and circulating tumor cells
- Conclusion
- Acknowledgments
- References
- 4
- Prognostic and predictive role of bone metastasis in NSCLC: risk factors and clinical implications
- Introduction
- Incidence of BMs in NSCLC patients
- Prognostic role
- Localization of BMs
- Histology and driver mutations
- Development of complications and performance status
- Treatments
- Predictive role
- Risk factors for bone metastasis
- Prognostic factors and predictive factors for bone progression
- Predictive factors for SRE development
- Clinical implication and treatment
- Conclusion
- References
- 5
- Brain metastases in breast cancer
- Introduction
- The basis of breast cancer brain metastasis
- The metastatic cascade
- Brain microenvironment and BC
- Neuroinflammation role in metastasis
- Signaling pathways involved in BM from BC
- Differences between the primary tumor cells and BM
- Risk factors for brain metastasis in breast cancer
- Diagnosis
- Treatment
- Prognosis
- Specific conditions
- Brain metastasis from breast cancer in BRCA mutation carriers