Unraveling the complexities of metastasis : transition from a segmented view to a conceptual continuum /

"Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognosti...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Farooqi, Ammad Ahmad, Zhaid Qureshi, Muhammad, Sabitaliyevi, Uteuliyev Yerzhan
Format: eBook
Language:English
Published: London, UK : Academic Press, 2022.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 0 0 |a Unraveling the complexities of metastasis :  |b transition from a segmented view to a conceptual continuum /  |c edited by Ammad Ahmad Farooqi, Muhammad Zahid Qureshi, Uteuliyev Yerzhan Sabitaliyevi. 
260 |a London, UK :  |b Academic Press,  |c 2022. 
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505 8 |a 2 -- Multiple roles of circulating tumor cells and exosomes in cancer metastasis: implications for therapeutic inter ... -- Introduction -- CTCs involvement in metastatic progression -- Strategies for isolation and enrichment of CTCs -- Characterization of CTCs -- Exosomes involvement in metastatic progression -- Strategies for detection, isolation, and enrichment of exosomes -- Characterization of exosomes -- Clinical impact of CTCs and exosomes -- Conclusions and future perspectives -- References 
505 8 |a 3 -- Diagnosis and treatment of metastatic prostate cancer: the role of imaging, liquid biopsies, and biomarkers for ... -- Introduction -- Overview of prostate cancer disease states and treatment options -- Proliferative inflammatory atrophy -- Localized prostate cancer and treatment options -- Metastatic castration-resistant prostate cancer and treatment options -- Improved imaging and image-guided biopsy for prostate cancer -- Imaging signatures of hypoxia -- Gene signature panels for prostate cancer risk stratification 
505 8 |a Next-generation sequencing and prostate cancer: cell-free nucleic acids and circulating tumor cells -- Conclusion -- Acknowledgments -- References -- 4 -- Prognostic and predictive role of bone metastasis in NSCLC: risk factors and clinical implications -- Introduction -- Incidence of BMs in NSCLC patients -- Prognostic role -- Localization of BMs -- Histology and driver mutations -- Development of complications and performance status -- Treatments -- Predictive role -- Risk factors for bone metastasis -- Prognostic factors and predictive factors for bone progression 
505 8 |a Predictive factors for SRE development -- Clinical implication and treatment -- Conclusion -- References -- 5 -- Brain metastases in breast cancer -- Introduction -- The basis of breast cancer brain metastasis -- The metastatic cascade -- Brain microenvironment and BC -- Neuroinflammation role in metastasis -- Signaling pathways involved in BM from BC -- Differences between the primary tumor cells and BM -- Risk factors for brain metastasis in breast cancer -- Diagnosis -- Treatment -- Prognosis -- Specific conditions -- Brain metastasis from breast cancer in BRCA mutation carriers 
520 |a "Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognostic analysis of different metastatic patterns in advanced cancer patients is becoming increasingly problematic. It is therefore essential to take a step back and focus on the underlying mechanisms of metastasis before moving ahead for effective translation of laboratory findings to clinically effective therapeutics. This book is surely helpful in putting together missing pieces of an incomplete jig-saw puzzle of molecular cancer. The book discusses topics such as the role of TRAIL-mediated signaling, late metastasis and mechanisms underlying tumor cell dormancy, CTCs and exomes, non-coding way of metastasis, and stem cells. Additionally, it brings relevant and updated information on nanotechnology-based docetaxel and the peculiarities of cancer cell metabolism."--  |c Title details screen. 
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