rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Chemical biology of the genome
  name:
    name part: Roy, Siddhartha
    name part: 1954-
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Kundu, Tapas K.
    role:
      role term: author.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2021
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xii, 337 pages) : illustrations
  abstract: "Chemical Biology of the Genome provides a comprehensive overview of essential concepts and principles of genomic and epigenomics dynamics as explored through the lens of chemical biology. Key examples and case studies illustrate chemical biology methods for study and analysis of the genome and epigenome, with an emphasis on relevance to physiological and pathophysiological processes and drug discovery. Authors and international leaders in biochemical studies of the genome, Drs. Siddhartha Roy and Tapas Kundu, adopt an integrated, interdisciplinary approach throughout, demonstrating how fast evolving chemical and mass-scale sequencing tools are increasingly used to interpret biochemical processes of the genome. Later sections discuss chemical modifications of the genome, DNA sequence recognition by proteins and gene regulation, GWAS and EpiGWAS studies, 3D architecture of the genome, and functional genome architecture. In-depth, discovery focused chapters examine intervention in gene networks using SiRNA/ShRNA, miRNA, and anti-miR, small molecule modulation of iPS, drug resistance pathways altered DNA methylation as drug targets, anti-miR as therapeutics, and nanodelivery of drugs. Offers an interdisciplinary discussion of the chemical biology of the genome and epigenome, employing illustrative case studies in both physiological and pathophysiological contexts"--
  table of contents: An integrative view of chemical biology -- Methods : tools for studying genomes and gene functions -- Genes, genomes, and genome dynamics -- Chemical modifications of genome -- Chemical principles of DNA sequence regulation and gene regulation -- Elucidation of genome sequence and functional architecture by chemical biology approach -- Chemical genomics : understanding gene regulatory networks in differentiation and disease -- Chemical biology : drug discovery targeting the functional genome.
  note: Siddhartha Roy, Tapas K. Kundu.
  note: Includes bibliographical references and index.
  subject:
    topic: Genomes
  subject:
    topic: Genomics
  subject:
    topic: Biochemistry
  subject:
    topic: Génomes
  subject:
    topic: Génomique
  subject:
    topic: Biochimie
  subject:
    topic: biochemistry
  subject:
    topic: Biochemistry
  subject:
    topic: Genomes
  subject:
    topic: Genomics
  classification: QH447
  classification: 572.863
  related item:
    title info:
      title: Chemical biology of the genome
    name:
      name part: Roy, Siddhartha.
    origin info:
      publisher: London, England : Academic Press, [2021]
    identifier: (OCoLC)1104693743
  identifier: 9780128176450
  identifier: 0128176458
  identifier: 9780128176443
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: YDX
    record creation date: 210519
    record change date: 20260327170222.9
    record identifier: in00005767998
    language of cataloging:
      language term: eng