http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Multifunctional theranostic nanomedicines in cancer
Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions--including targeting, imaging, and therapy--have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer.- Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines- Discusses treatment options from a pharmaceutical sciences perspective- Includes translational science and targeted CNS cancer treatment.
Front Cover -- Multifunctional Theranostic Nanomedicines in Cancer -- Copyright Page -- Contents -- List of contributors -- 1 Nanoparticle-based theranostics in cancer -- 1.1 Introduction -- 1.2 Fundamental of nanotheranostics for diagnosis and therapy -- 1.3 Nanoparticles in the treatment of cancer theranostics -- 1.3.1 Organic nanoparticles -- 1.3.1.1 Liposomes -- 1.3.1.2 Solid lipid nanoparticles -- 1.3.1.3 Polymeric dendrimers -- 1.3.1.4 Polymeric micelles -- 1.3.1.5 Polymer-drug conjugate -- 1.3.2 Inorganic nanoparticles -- 1.3.2.1 Iron oxide nanoparticles -- 1.3.2.2 Gold nanoparticles
1.3.2.3 Silica nanoparticles -- 1.3.2.4 Gadolinium nanoparticles -- 1.3.2.5 Carbon nanotubes -- 1.3.2.6 Quantum dots -- 1.4 Imaging guidance used in nanotheranostics -- 1.4.1 Optical imaging -- 1.4.2 Magnetic resonance imaging -- 1.4.3 Computed tomography -- 1.4.4 Positron emission tomography (PET) -- 1.4.5 Single-photon emission computed tomography (SPECT) -- 1.4.6 Ultrasonic imaging -- 1.5 Role of nanotheranostics in cancer treatment -- 1.5.1 Strategies of nanotheranostics for cancer treatment -- 1.5.1.1 Passive targeting -- 1.5.1.2 Active targeting -- 1.5.1.3 Stimuli-responsive targeting
1.5.1.3.1 pH as stimuli -- 1.5.1.3.2 Redox reactions -- 1.5.1.3.3 Hypoxia -- 1.5.1.3.4 Enzyme-responsive nanotheranostic agent -- 1.5.1.3.5 Temperature-stimulated nanotheranostics -- 1.5.1.3.6 Photo/light-triggered nanotheranostics -- 1.5.1.3.7 Magnetic field-triggered nanotheranostics -- 1.5.1.3.8 Ultrasound-triggered nanotheranostics -- 1.6 Clinical application of nanotheranostics -- 1.7 Conclusion and future perspective -- Conflict of interest -- References -- 2 Multifunctional nanotheranostics for cancer diagnosis and treatments -- 2.1 Introduction -- 2.2 Imaging modalities
2.2.1 Optical imaging -- 2.2.1.1 NIRF imaging -- 2.2.1.2 Surface enhanced Raman spectroscopy imaging -- 2.2.2 Magnetic resonance imaging -- 2.2.2.1 Gd-based nanoparticles -- 2.2.2.2 Iron oxide contrast agent -- 2.2.3 Nuclear (radionuclide based) imaging -- 2.2.3.1 Single photo emission computed tomography -- 2.2.3.2 Positron emission tomography -- 2.2.4 Ultrasound-based imaging -- 2.3 Different multifunctional nanocarriers used as theranostic system -- 2.3.1 Polymer conjugates -- 2.3.2 Dendrimers -- 2.3.3 Polymeric micelles -- 2.3.4 Superparamagnetic iron oxide nanoparticles -- 2.3.5 Quantum dots
2.3.6 Carbon dots (graphene quantum dots) -- 2.3.7 Gold nanostructures -- 2.3.8 Stimuli responsive -- 2.3.8.1 Temperature sensitive -- 2.3.8.2 pH sensitive -- 2.3.8.3 Ultrasound responsive -- 2.4 Conclusions -- Acknowledgment -- Conflict of interest -- References -- 3 Multifunctional micellar nanomedicine for cancer therapy -- 3.1 Introduction -- 3.2 Polymeric micelles -- 3.2.1 Structure and composition of micelles -- 3.2.2 Advantage of polymeric micelles -- 3.3 Advanced functions of micellar nanomedicine -- 3.3.1 Active targeting -- 3.3.2 Passive targeting