Protein kinases in drug discovery /

Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by chemically adding phosphate groups to them. New chapters in this release include Transport Proteins and AMPs: Implications in Human Disease, Protein kinase CK2 inhi...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Donev, Rossen
Format: eBook
Language:English
Published: Cambridge, MA : Academic Press, 2021.
Series:Advances in protein chemistry and structural biology ; v. 124.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by chemically adding phosphate groups to them. New chapters in this release include Transport Proteins and AMPs: Implications in Human Disease, Protein kinase CK2 inhibition as a pharmacological strategy, Emerging role of Protein kinase in diabetes mellitus: From Mechanism to therapy, Dual Roles of ATP-binding site in Protein Kinases: Orthosteric inhibition and Allosteric Regulation, Pseudokinases in drug discovery and development: progress, challenges and future prospects, Comparison of knowledge-based vs. combinatorial peptide library approaches for the identification of protein kinase substrates, and more.- Contains timely chapters written by well-renown authorities in their field- Includes a number of high-quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students- Integrates experimental and computational methods for studying the role of protein kinases in different diseases, along with sections on the design of suitable protein kinase inhibitors for use in the treatment of patients.
Physical Description:1 online resource
ISBN:9780323853149
0323853145