Quadruplex nucleic acids as targets for medicinal chemistry /
"The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic...
| Corporate Author: | |
|---|---|
| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
Amsterdam, The Netherlands :
Elsevier Academic Press,
2020.
|
| Edition: | First edition. |
| Series: | Annual reports in medicinal chemistry ;
v. 54. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | "The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials."--Publisher's web page, viewed August 26, 2020 |
|---|---|
| Physical Description: | 1 online resource (xviii, 546 pages) : illustrations (some colour) |
| Bibliography: | Includes bibliographical references. |
| ISBN: | 9780128210185 0128210184 |
| ISSN: | 0065-7743 ; |