Cover Image

Physiologically based pharmacokinetic (PBPK) modeling : methods and applications in toxicology and risk assessment /

Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, clas...

Full description

Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Fisher, Jeffrey W., Gearhart, Jeffery M., Lin, Zhoumeng
Format: eBook
Language:English
Published: London ; San Diego, CA : Academic Press, [2020]
Subjects:
Pharmacokinetics > Simulation methods.
Pharmacokinetics.
Pharmacokinetics
Pharmacocinétique > Méthodes de simulation.
Pharmacocinétique.
Electronic books.
Online Access:Connect to the full text of this electronic book
Description
Summary:Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro information, and in silico methods. There are end-of-chapter exercises that allow readers to practice and learn the skills associated with PBPK modeling, dose-response, and its applications to safety and risk assessments.
Item Description:Includes index.
Physical Description:1 online resource
ISBN:9780128196823
0128196823