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Molecular biology of neurodegenerative diseases
"Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Volume 168 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, Propagation and removal of cerebral amyloid angiopathy, and much more."--
Preface / David B. Teplow -- Section I: Targetting AD. Chapter One. Fluid biomarker-based molecular phenotyping of Alzheimer's disease patients in research and clinical settings / Kaj Blennow, Henrik Zetterberg -- Chapter Two. Tracking down a missing trigger for Alzheimer's disease by mass spectrometric imaging based on brain network analysis / Minako Hoshi -- Chapter Three. Using mirror-image peptides to enhance robustness and reproducibility in studying the amyloid [beta]-protein / Ariel J. Kuhn, Jevgenij A. Raskatov -- Section II: Etiology of AD. Chapter Four. In search of pathogenic amyloid [beta]-peptide in familial Alzheimer's disease / Michael S. Wolfe -- Chapter Five. Biology of splicing in Alzheimer's disease research / Kenichi Nagata, Takashi Saito, Takaomi C. Saido, Takashi Morihara -- Chapter Six. Acquired cerebral amyloid angiopathy: an emerging concept / Masahito Yamada, Tsuyoshi Hamaguchi, Kenji Sakai -- Section III: Neuroimmunology of AD. Chapter Seven. Blood-brain barrier and innate immunity in the pathogenesis of Alzheimer's disease / Goran Šimić, Ena Španić, Lea Langer Horvat, Patrick R. Hof -- Chapter Eight. Gut microbiota mediated allostasis prevents stress-induced neuroinflammatory risk factors of Alzheimer's disease / Susan Westfall, Umar Iqbal, Maria Sebastian, Giulio Maria Pasinetti -- Chapter Nine. Neuroimmune interactions in Alzheimer's disease-New frontier with old challenges? / Stefan Prokop, Virginia M.Y. Lee, John Q. Trojanowski -- Section IV: AD therapy. Chapter Ten. Alzheimer's therapy development: a few points to consider / Einar M. Sigurdsson -- Chapter Eleven. The next steps in curing Alzheimer's disease / Fred W. van Leeuwen -- Chapter Twelve. Future horizons in Alzheimer's disease research / Thomas Wisniewski, Eleanor Drummond -- Chapter Thirteen. Why delay in effective treatment for Alzheimer's disease and related conditions / Khalid Iqbal, Fei Liu, ChengXin Gong, Chunling Dai, Wen Hu -- Chapter Fourteen. Restoring synaptic function through multimodal therapeutics / Raul Loera-Valencia, Muhammad-Al-Mustafa Ismail, Per Nilsson, Bengt Winblad -- Chapter Fifteen. Disease-modifying therapy for proteinopathies: can the exception become the rule? / Gal Bitan -- Chapter Sixteen. Combination therapy for Alzheimer's disease and related dementias / Martin M. Bednar -- Section V: Alpha-synucleinopathies. Chapter Seventeen. Can infections trigger alpha-synucleinopathies? / Christopher T. Tulisiak, Gabriela Mercado, Wouter Peelaerts, Lena Brundin, Patrik Brundin -- Chapter Eighteen. Prion-like propagation of [alpha]-synuclein in neurodegenerative diseases / Airi Tarutani, Masato Hasegawa -- Section VI: Model systems. Chapter Nineteen. Yeast models of neurodegenerative diseases / Mick F. Tuite.
Molecular biology of neurodegenerative diseases : Part A
Cambridge, MA : Elsevier Academic Press, [2019]
Progress in molecular biology and translational science ; Volume 168