Small Molecule Drug Discovery : Methods, Molecules and Applications /

Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Trabocchi, Andrea (Editor), Lenci, Elena (Editor)
Format:	eBook
Language:	English
Published:	Amsterdam, Netherlands ; Cambridge, MA : Elsevier, [2020]
Subjects:	Drug development. Bioactive compounds. Médicaments > Développement. Composés bioactifs. Bioactive compounds Drug development Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

1 Synthetic approaches toward small molecule libraries
2 Chemical reactions for building small molecules
3 Chemoinformatics approaches to assess chemical diversity and complexity of small molecules
4 Virtual screening of small-molecule libraries
5 Screening and biophysics in small molecule discovery
6 Principles and applications of small molecule peptidomimetics
7 sp2-Iminosugars as chemical mimics for glycodrug design
8 Synthesis and biological properties of spiroacetal-containing small molecules
9 Centrocountins--synthesis and chemical biology of nature inspired indoloquinolizines
10 PPIs as therapeutic targets for anticancer drug discovery: the case study of MDM2 and BET bromodomain inhibitors
11 Discovery of small molecules for the treatment of Alzheimer's disease