rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: GABAb receptor pharmacology
    sub title: a tribute to Norman Bowery
  name:
    name part: Blackburn, Thomas.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: festschrift
  genre: Electronic books.
  genre: Festschriften
  genre: Festschriften.
  origin info:
    place:
      place term: ne
    place:
      place term: Amsterdam
    place:
      place term: Boston
    publisher: Elsevier
    date issued: 2010
    edition: 1st ed.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (521 pages)
  abstract: This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational, in the discovery of drugs acting at the GABAB receptor. The topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecu.
  table of contents: Cover; GABAB Receptor Pharmacology: A Tribute to Norman Bowery; Copyright; Contents; Contributors; Preface; Historical Perspective and Emergence of the GABAB Receptor; Abstract; I. Introduction; II. GABAB Receptor Ligands; III. Receptor Distribution; IV. Allosteric Modulation; V. Receptor Function; VI. Potential Therapeutic Significance; VII. Conclusion; References; Chemistry and Pharmacology of GABAB Receptor Ligands; Abstract; I. Introduction; II. GABAB Receptor Agonists; III. GABAB Receptor Partial Agonists; IV. Positive Modulators of GABAB Receptors; V. GABAB Receptor Antagonists
  table of contents: VI. ConclusionAcknowledgments; List of Nonstandard Abbreviations; References; Heterodimerization of the GABAB Receptor-Implications for GPCR Signaling and Drug Discovery; Abstract; I. Introduction; II. Identification of the GABAB Receptors; III. The Phylogeny of GABAB Receptors GABAB Receptors in DifferentSpecies; IV. Structure of GABAB Receptors; V. Function of the GABAB Receptor Heterodimer; VI. GABAB as a Model System for GPCR Dimerization; VII. Conclusions; Abbreviations; References; Mechanisms of GABAB Receptor Exocytosis, Endocytosis, and Degradation; Abstract; I. Introduction
  table of contents: II. Cell-Surface Trafficking of GABAB ReceptorsIII. Endocytosis of GABAB Receptors; IV. Degradation of GABAB Receptors; V. Conclusions; Acknowledgments; Abbreviations; References; Functional Modulation of GABAB Receptors by ProteinKinases and Receptor Trafficking; Abstract; I. Introduction; II. Phosphorylation of GABABR and Its Functional Modulation; III. Phosphorylation-Independent Desensitization of GABABRs by ProteinKinases; IV. GABABR Endocytic Sorting and the Control of Receptor Cell SurfaceStability; V. GABABR Phosphorylation and Diseases; VI. Conclusion; Acknowledgments; Abbreviations
  table of contents: III. Possible Ligands for GABABR in Cerebellar Purkinje CellsIV. Functions of GABABR Near the Excitatory Synapses; V. Possible Physiological Significance of GABABR-Mediated Effects onmGluR1 Signaling; VI. Conclusion; Acknowledgments; Non-standard abbreviations; References; GABA Transporter GAT1: A Crucial Determinant of GABAB Receptor Activation in Cortical Circuits?; Abstract; I. Introduction; II. The Plasma Membrane GABA Transporter; III. Cellular and Subcellular Localization of GABABRsand GAT1; IV. GABABR Activation by GABA Released from EndogenousSources
  note: edited by Thomas P. Blackburn. Volume 58.
  note: V. GAT1 Activity and GABABR Activation
  note: ReferencesGABAB Receptor Coupling to G-proteins and Ion Channels; Abstract; I. Introduction; II. GABAB Receptor Structure; III. GABAB Receptor Protein Expression; Iv. GABAB Receptor Effectors; V. Formation of a Macromolecular Signaling Heterocomplex; VI. GABAB Receptor-Dependent Desensitization; VII. Conclusion; Abbreviations; References; GABAB Receptor-Mediated Modulation of Metabotropic Glutamate Signaling and Synaptic Plasticity in Central Neurons; Abstract; I. Introduction; II. Synaptic Organization Around Cerebellar Purkinje Cells
  note: English.
  note: Includes bibliographical references and index.
  subject:
    name:
      name part: Bowery, N. G
  subject:
    topic: GABA
    topic: Receptors
  subject:
    topic: Pharmacology
  subject:
    topic: Receptors, GABA-B
    topic: chemistry
  subject:
    topic: Receptors, GABA-B
    topic: physiology
  subject:
    topic: gamma-Aminobutyric Acid
    topic: pharmacology
  subject:
    topic: Pharmacology
  subject:
    topic: Pharmacologie
  subject:
    topic: pharmacology
  subject:
    topic: MEDICAL
    topic: Pain Medicine
  subject:
    topic: MEDICAL
    topic: Psychiatry
    topic: Psychopharmacology
  subject:
    topic: GABA
    topic: Receptors
  subject:
    topic: Pharmacology
  classification: QP563.G32 G33 2010
  classification: 615.78
  classification: QU 60 .G1126 2010
  related item:
    title info:
      title: Advances in pharmacology
  related item:
    title info:
      title: Advances in pharmacology
    identifier: 1557-8925
    identifier: (CKB)954927720456
    identifier: (DLC) 2005215191
    identifier: (OCoLC)60626730
  identifier: 1282770039
  identifier: 9781282770034
  identifier: 9786612770036
  identifier: 6612770031
  identifier: 0123786487
  identifier: 9780123786487
  identifier: 9780123786470
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: SFB
    record creation date: 101013
    record change date: 20260327163634.6
    record identifier: in00005765673
    language of cataloging:
      language term: eng