rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: A
    title: pharmacology primer
    sub title: techniques for more effective and strategic drug discovery
  name:
    name part: Kenakin, Terrence P.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2019
    copyright date: 2019
    edition: Fifth edition.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource : illustrations (some color)
  abstract: A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research.
  table of contents: What is pharmacology? -- How different tissues process drug response -- Drug-receptor theory -- Pharmacological assay formats : binding -- Agonists : the measurement of affinity and efficacy in functional assays -- Orthosteric drug antagonism -- Allosteric modulation -- The optimal design of pharmacological experiments -- Pharmacokinetics -- Safety pharmacology -- The drug discovery process -- Statistics and experimental design -- Selected pharmacological methods -- Exercises in pharmacodynamics and pharmacokinetics.
  note: Terry P. Kenakin, PhD, Professor, Department of Pharmacology, University of North Carolina School of Medicine, United States.
  note: Includes bibliographical references and index.
  subject:
    topic: Pharmacology, Experimental
  subject:
    topic: Drugs
    topic: Dose-response relationship
  subject:
    topic: Receptors, Drug
    topic: physiology
  subject:
    topic: Dose-Response Relationship, Drug
  subject:
    topic: Pharmacology
    topic: methods
  subject:
    topic: Pharmacologie expérimentale
  subject:
    topic: Médicaments
    topic: Relations dose-effet
  subject:
    topic: MEDICAL
    topic: Pharmacology
  subject:
    topic: Drugs
    topic: Dose-response relationship
  subject:
    topic: Pharmacology, Experimental
  classification: RM301.25
  classification: 615/.7
  classification: QV 36
  related item:
    title info:
      title: Pharmacology primer
    name:
      name part: Kenakin, Terrence P.
    origin info:
      publisher: London, United Kingdom ; San Diego, CA : Academic Press, an imprint of Elsevier, [2019]
      edition: Fifth edition.
    identifier: (OCoLC)1037806446
  identifier: 9780128139585
  identifier: 0128139587
  identifier: 9780128139578
  identifier: 0128139579
  identifier: 9780128139585 Ingram Content Group
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: N$T
    record creation date: 181101
    record change date: 20260327154034.9
    record identifier: in00005764049
    language of cataloging:
      language term: eng