rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Human Population Genetics and Genomics
  name:
    name part: Templeton, Alan Robert
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2018
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed.
  table of contents: Front Cover; Human Population Genetics and Genomics; Human Population Genetics and Genomics; Copyright; Dedication; Contents; Preface; 1 -- DEFINITION, SCOPE, AND PREMISES OF HUMAN POPULATION GENETICS; THE BASIC PREMISES OF POPULATION GENETICS; PREMISE 1: DNA CAN REPLICATE; PREMISE 2: DNA CAN MUTATE AND RECOMBINE; PREMISE 3: DNA AND THE ENVIRONMENT INTERACT TO PRODUCE PHENOTYPES; NATURAL SELECTION AND THE INTEGRATION OF THE THREE PREMISES; REFERENCES; 2 -- THE HUMAN GENOME; COMPONENTS OF THE NUCLEAR GENOME; GENES; TRANSPOSABLE ELEMENTS; REPETITIVE DNA; CG ISLANDS; CENTROMERES; TELOMERES.
  table of contents: THE TRANSCRIPTOMETHE EXOME, SPLICEOSOME, AND PROTEOME; EPIGENOME; THE MITOCHONDRIAL GENOME; MUTATION AND RECOMBINATION IN THE HUMAN GENOMES; MUTATION; RECOMBINATION; REFERENCES; 3 -- SYSTEMS OF MATING; RANDOM MATING AND THE HARDY-WEINBERG LAW; INBREEDING; PEDIGREE INBREEDING; SYSTEM OF MATING INBREEDING; ASSORTATIVE MATING; DISASSORTATIVE MATING; COEXISTENCE OF MULTIPLE SYSTEMS OF MATING WITHIN A DEME; REFERENCES; 4 -- GENETIC DRIFT; THE FATE OF A NEWLY ARISEN MUTATION IN A LARGE POPULATION; GENETIC DRIFT IN A FINITE POPULATION; EFFECTIVE POPULATION SIZES.
  table of contents: GENETIC DRIFT AND LINKAGE DISEQUILIBRIUMGENETIC DRIFT AND NEUTRAL MUTATIONS; REFERENCES; 5 -- A BACKWARD VIEW OF GENETIC DRIFT: COALESCENCE; BASIC COALESCENT MODEL; COALESCENCE WITH MUTATION; HAPLOTYPE TREES; HAPLOTYPE TREES, POPULATION TREES, AND SPECIES TREES; COALESCENCE AND RECOMBINATION; REFERENCES; 6 -- GENE FLOW AND SUBDIVIDED POPULATIONS; A TWO-DEME MODEL OF GENE FLOW; THE BALANCE OF GENE FLOW AND GENETIC DRIFT; GENDER-BIASED GENE FLOW; SYSTEM OF MATING AND GENE FLOW; KIN-STRUCTURED MIGRATION; ADMIXTURE; ISOLATION BY DISTANCE AND RESISTANCE; IDENTIFYING HUMAN SUBPOPULATIONS.
  table of contents: POPULATION SUBDIVISION, ISOLATION-BY-DISTANCE, AND EFFECTIVE POPULATION SIZESREFERENCES; 7 -- HUMAN POPULATION HISTORY OVER THE LAST TWO MILLION YEARS; HAPLOTYPE TREES AS A WINDOW INTO THE PAST; POPULATION TREES; ANCIENT DNA-THE ORIGINS OF THE HUMAN GENE POOL; ANCIENT DNA-THE LAST 25,000YEARS; REFERENCES; 8 -- GENOTYPE AND PHENOTYPE; FISHER'S QUANTITATIVE GENETIC MODEL; CLASSICAL HUMAN QUANTITATIVE GENETIC ANALYSIS; MEASURED GENOTYPE APPROACHES TO QUANTITATIVE GENETICS; LINKAGE MAPPING; RUNS OF HOMOZYGOSITY; ADMIXTURE MAPPING; GENOME-WIDE ASSOCIATION STUDIES.
  table of contents: CLASSICAL QUANTITATIVE GENETICS VERSUS MEASURED GENOTYPE APPROACHESREFERENCES; 9 -- NATURAL SELECTION; A ONE-LOCUS, TWO-ALLELE MODEL OF NATURAL SELECTION; SICKLE-CELL AND MALARIAL ADAPTATIONS: AN EXAMPLE OF THE MEASURED GENOTYPE APPROACH TO NATURAL SELECTION; A QUANTITATIVE GENETIC, UNMEASURED GENOTYPE MODEL OF NATURAL SELECTION; REFERENCES; 10 -- DETECTING SELECTION THROUGH ITS INTERACTIONS WITH OTHER EVOLUTIONARY FORCES; INTERACTION OF SELECTION WITH MUTATION; INTERACTIONS OF SELECTION WITH MUTATION AND GENETIC DRIFT; INTERACTIONS OF SELECTION WITH MUTATION, GENETIC DRIFT, AND RECOMBINATION.
  note: Alan R. Templeton.
  note: Includes bibliographical references and index.
  subject:
    topic: Human population genetics
  subject:
    topic: Human genetics
  subject:
    topic: Electronic books
  subject:
    topic: Génétique des populations humaines
  subject:
    topic: Génétique humaine
  subject:
    topic: Livres numériques
  subject:
    topic: e-books
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Evolution
  subject:
    topic: Human genetics
  subject:
    topic: Human population genetics
  classification: GN289
  classification: 576.58
  related item:
    title info:
      title: Human Population Genetics and Genomics
    name:
      name part: Templeton, Alan Robert.
    origin info:
      publisher: London : Academic Press, 2018
    identifier: (OCoLC)1040622590
  identifier: 9780123860262
  identifier: 0123860261
  identifier: 9780123860255
  identifier: 0123860253
  identifier: 9780123860262 Ingram Content Group
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: N$T
    record creation date: 181113
    record change date: 20260327154023.3
    record identifier: in00005763933
    language of cataloging:
      language term: eng