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Management of high altitude pathophysiology
Management of High Altitude Pathophysiology presents a comprehensive overview on the various therapeutic practices and ongoing research relating to the development of more potent and novel formulations for managing high altitude pathophysiology. It provides a detailed application of both herbal and non-herbal therapeutic agents, including their nanoformulations. This important reference provides benefits to the medical and herbal scientific communities, doctors treating patients with high altitude complications, individuals travelling to high altitudes for recreation or work, and scientists working on future drug development.
Front Cover; Management of High Altitude Pathophysiology; Copyright; Dedication; Contents; Contributors; Preface; SECTION I: Human Performance at High Altitude; Chapter 1: High Altitude and Hypoxia; 1.1. Introduction; 1.2. High Altitudes: Worldwide Scenario; 1.3. High Altitudes Environment and Hypoxia; 1.3.1. Defining the Term ``Hypoxia;́́ 1.3.2. Types of Hypoxia; 1.4. Hypobaric Hypoxia and Physiology; 1.5. Conclusion; Chapter 2: High Altitude Ailments: Causes and Effects; 2.1. Introduction; 2.1.1. Hypobaric Hypoxia at High Altitudes
2.1.2. Physiological Adaptations at High Altitudes: The Acclimatization Process2.1.3. Physical Factors at High Altitudes; 2.2. High-Altitude Ailments; 2.2.1. Acute Mountain Sickness; 2.2.2. High Altitude-Induced Headache; 2.2.3. High-Altitude Cerebral Edema; 2.2.4. High-Altitude Pulmonary Edema; 2.2.5. High-Altitude Retinopathy; 2.2.6. Sleep Disturbance; 2.2.7. Existing Medical Conditions as Risk Factors at High Altitudes; 2.3. Conclusions; Section II: Herbal Therapeutics for High Altitude Problems; Chapter 3: Hippophae sp.: A Boon for High-Altitude Maladies; 3.1. Introduction
3.2. History and Traditional Usage3.3. Botanical Description and Natural Distribution; 3.4. Hippophae Species; 3.4.1. Hippophae rhamnoides; 3.4.2. Hippophae tibetana; 3.4.3. Hippophae neurocarpa; 3.4.4. Hippophae gyantsensis; 3.4.5. Hippophae goniocarpa; 3.4.6. Hippophae salicifolia; 3.5. Chemical Constituents of H. rhamnoides; 3.5.1. Carbohydrates; 3.5.2. Lipids; 3.5.3. Organic Acids and Other Volatile Compounds; 3.5.4. Polyphenolic Compounds; 3.5.5. Proteins and Amino Acids; 3.5.6. Vitamins and Minerals; 3.6. Bioactivities of H. rhamnoides; 3.6.1. Antihypoxic Effects
3.6.2. Antioxidant Activity3.6.3. Cardioprotective Action; 3.6.4. Hepatoprotective Action; 3.6.5. Anticarcinogenic Activity; 3.6.6. Antimicrobial Effect; 3.6.7. Antiinflammatory Effect; 3.6.8. Dermatological Activity; 3.6.9. Platelet Aggregation Activity; 3.6.10. Radioprotective Effect; 3.7. Health and Nutritional Products From H. rhamnoides; 3.7.1. Contributions by DIHAR, Leh; 3.7.2. Contributions by DFRL, Mysore; 3.7.3. Contributions by DIPAS, Delhi; 3.8. Conclusions; Chapter 4: Valeriana sp.: The Role in Ameliorating High-Altitude Ailments; 4.1. Introduction; 4.2. Description of the Plant
4.3. Geographical Distribution and Habitat4.4. Active Constituents in V. wallichii; 4.5. Biological Activities of V. wallichii; 4.6. Applications of V. wallichii in Improving Health at High Altitudes; 4.6.1. Anxiolytic and Antidepressant; 4.6.2. Insomnia; 4.6.3. Antispasmodic Activity; 4.6.4. Antipsychotic Activity; 4.6.5. Anticonvulsant Activity; 4.6.6. Antioxidant Activity; 4.6.7. Analgesic Activity; 4.6.8. Antiinflammatory Activity; 4.6.9. Radioprotective Activity; 4.6.10. Adaptogenic Activity; 4.7. Conclusions; Chapter 5: Rhodiola sp.: The Herbal Remedy for High-Altitude Problems
edited by Kshipra Misra, Priyanka Sharma, Anuja Bhardwaj.
Includes bibliographical references and index.