rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Gnotobiotics
  name:
    name part: Schoeb, Trenton R.
    role:
      role term: editor
    role:
      role term: edt
  name:
    name part: Eaton, Kathryn A.
    role:
      role term: editor
    role:
      role term: edt
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  genre: Internet Resources.
  origin info:
    place:
      place term: enk
    date issued: 2017
    copyright date: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xiii, 414 pages) : illustrations (chiefly color
  abstract: Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal speciesAnalyzes microbiota in numerous contextsPresents detailed coverage of the protocols and operation of a gnotobiotic facility.
  table of contents: Front Cover; Gnotobiotics; Dedication; Gnotobiotics; Copyright; Contents; List of Contributors; Foreword; 1 -- Historical Overview; REFERENCES; 2 -- PRINCIPLES OF ESTABLISHING AND OPERATING A GNOTOBIOTIC FACILITY*; 1. INTRODUCTION; 2. INSTITUTIONAL FACTORS; 2.1 Financial Support; 2.2 Space Requirements; 2.3 Autoclave; 2.4 Personnel; 2.5 Microbiology Laboratory; 2.6 Facility Productivity and Experimental Utilization; 2.7 Facility Operation and Compliance; 3. ISOLATOR SELECTION; 3.1 Isolator Types and Construction; Chamber; Air Supply; Transfer Port; Gloves
  table of contents: 3.2 Individual Positive Pressure Cage Systems4. STERILIZATION; 4.1 Steam; 4.2 Ionizing Radiation; 4.3 Liquid Chemical; Peracetic (Peroxyacetic, Ethaneperoxoic) Acid; Chlorine Dioxide; Other Liquid Products; Application of Liquid Sterilants; Monitoring Liquid Sterilization; 4.4 Gas and Vapor Chemical; 4.5 Dry Heat; 4.6 Filtration; 4.7 Further Information; 5. OPERATION; 5.1 Standard Operating Procedures; 5.2 Isolator Setup; Cleaning and Inspection; Leak Testing; Sterilization; 5.3 Sterilization and Entry of Supplies; Sterilizing Cylinders and Packs; Food; Water; Other Materials and Supplies
  table of contents: Port Sterilization5.4 Introduction and Transfer of Animals; 5.5 Working in Isolators; 5.6 Monitoring for Contamination; Sources of Contamination; Inspection and Observation; Microbiological Monitoring; Sampling; Fecal Wet Mounts and Gram Staining; Culture; Molecular Methods; Serologic Testing; Frequency of Monitoring; Summary; 5.7 Derivation of Germfree Mice; Hysterotomy and Hysterectomy; Embryo Transfer; 5.8 Establishing Defined Microbiota; Altered Schaedler Flora; Other Microbiota; 6. RESOURCES; 6.1 Recommended Reading; Gnotobiotics; Sterilization; 6.2 Online; 6.3 Manufacturers
  table of contents: 6.4 LaboratoriesGLOSSARY; REFERENCES; 3 -- PROCEDURES FOR RODENTS*; 1. INTRODUCTION; 2. BACKGROUND AND ACKNOWLEDGMENTS; 2.1 University of Texas Southwestern Medical Center (UT Southwestern); 2.2 University of Michigan (Michigan); 2.3 University of Alabama at Birmingham (UAB); 2.4 Baylor College of Medicine (BCM); 3. GENERAL INFORMATION; 3.1 UT Southwestern; Equipment; Access; Compliance; 3.2 UAB; Equipment; Staff; General Work Practices; Access; Compliance; 3.3 BCM; Equipment; Staff; Access; Compliance; 4. STERILIZATION AND STERILIZATION MONITORING; 4.1 UT Southwestern; Autoclaving
  table of contents: Quality AssuranceCycles; Liquid Sterilization; 4.2 UAB; Autoclaving; General; Quality Assurance; Cycles; Liquid Sterilization; General; Sterilants; Quality Assurance; Sprayer (Atomizer); Air Hose Connection; Maintenance; 4.3 BCM; Autoclaving; Liquid Sterilization; 5. STERILIZING CYLINDERS; 5.1 UT Southwestern; Filter Medium Installation and Replacement; Equipment and Supplies; Procedure; Cylinder Maintenance; Supply Cylinders; Equipment and Supplies; Procedure; Packing Drawstring Bags; Equipment and Supplies; Procedure for Food; Procedure for Bedding
  note: edited by Trenton R. Schoeb, Kathryn A. Eaton.
  note: Includes bibliographical references and index.
  subject:
    topic: Germfree life
  subject:
    topic: Germ-Free Life
  subject:
    topic: Animals
  subject:
    topic: Gnotobiologie
  subject:
    topic: TECHNOLOGY & ENGINEERING
    topic: Agriculture
    topic: Animal Husbandry
  subject:
    topic: Germfree life
  classification: QH324.4 .G56 2017
  classification: 636.08/3
  classification: 2018 I-120
  classification: QY 58
  related item:
    title info:
      title: Gnotobiotics
    origin info:
      publisher: London : Academic Press, an imprint of Elsevier, [2017]
    identifier: (OCoLC)974698900
  related item:
    title info:
      title: American College of Laboratory Animal Medicine series
  identifier: 9780128045831
  identifier: 0128045833
  identifier: 9780128045619
  identifier: 0128045612
  identifier: 1026701 MIL
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: YDX
    record creation date: 170908
    record change date: 20260327152836.9
    record identifier: in00005762879
    language of cataloging:
      language term: eng