rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Research in the biomedical sciences
    sub title: transparent and reproducible
  name:
    name part: Williams, Michael
    role:
      role term: editor.
  name:
    name part: Curtis, Michael J.
    role:
      role term: editor.
  name:
    name part: Mullane, Kevin
    role:
      role term: editor.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  genre: Internet Resources.
  origin info:
    place:
      place term: enk
    date issued: 2018
    copyright date: 2018
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: Research in the Biomedical Sciences: Transparent and Reproducible documents the widespread concerns related to reproducibility in biomedical research and provides a best practices guide to effective and transparent hypothesis generation, experimental design, reagent standardization (including validation and authentication), statistical analysis, and data reporting. The book addresses issues in the perceived value of the existing peer review process and calls for the need for improved transparency in data reporting. It reflects new guidelines for publication that include manuscript checklists, replication/reproducibility initiatives, and the potential consequences for the biomedical research community and societal health and well-being if training, mentoring, and funding of new generations of researchers and incentives for publications are not improved. This book offers real world examples, insights, and solutions to provide a thought-provoking and timely resource for all those learning about, or engaged in, performing and supervising research across the biomedical sciences.
  table of contents: Cover -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- References -- Chapter 1 -- Reproducibility in Biomedical Research -- 1.1 -- Introduction -- 1.2 -- Defining Reproducibility -- 1.2.1 -- A New Lexicon for Reproducibility -- 1.2.1.1 -- Methods Reproducibility -- 1.2.1.2 -- Results Reproducibility -- 1.2.1.3 -- Inferential Reproducibility -- 1.2.1.4 -- Bayesian Paradigms in Reproducibility -- 1.3 -- Discipline Specific Terminology in the Biomedical Sciences?
  table of contents: 1.4 -- Experimental Factors in Addition to Statistics That Affect Reproducibility1.4.1 -- Unknown Unknowns Affecting Reproducibility -- 1.4.1.1 -- The Crabbe Mouse Study -- 1.4.1.2 -- Reproducibility Confounds in RNA Interference -- 1.4.1.3 -- Caenorhabditis Lifespan -- 1.4.2 -- Known Unknowns: Tacit Expertize -- 1.4.3 -- Diminishing Effects: Regression to the Mean -- 1.4.4 -- Overinterpretation of Effects on Secondary Endpoints in Studies -- 1.5 -- The Impact of the Internet on the Evolution of Research Practicesâ#x80;#x94;Databases and Third Party Analyses -- 1.5.1 -- Data Input
  table of contents: 1.5.2 -- Data Curation1.5.3 -- Cross-Database Integration -- 1.5.4 -- Analytical Tools -- 1.6 -- The Reproducibility Problem -- 1.6.1 -- Factors Contributing to the Reproducibility Problem -- 1.6.2 -- Human Contributions to the Reproducibility Problem -- 1.6.2.1 -- Litigation in Basic Biomedical Research -- 1.6.3 -- The Impact of the Internet on Publishing and Disseminating Information -- 1.6.3.1 -- High and Low Profile Journals -- 1.7 -- The Literature on Reproducibility in Biomedical Research -- 1.7.1 -- An Age-Old Concern -- 1.7.2 -- Concerns in the 21st Century
  table of contents: 1.7.3 -- Reproducibility in the 21st Century: Origins, Scope and Momentum1.7.3.1 -- Why Most Published Research Findings are False -- 1.7.3.2 -- Believe it or not: How Much can we Rely on Published Data on Potential Drug Targets? -- 1.7.3.3 -- Drug Development: Raise Standards for Preclinical Cancer Research -- 1.7.3.4 -- Reproducibility: An Academic Viewpoint -- 1.7.3.5 -- Reproducibility in the Psychological Sciences -- 1.7.3.6 -- Researcher Awareness of Fraud -- 1.8 -- Is There a Reproducibility Crisis? -- 1.9 -- Trouble at the Laboratory? -- 1.10 -- Retractions
  table of contents: 1.10.1 -- RetractionWatch1.10.2 -- Continued Citation of Retracted Publications -- 1.10.3 -- The Spectrum of Irreproducibility -- 1.10.4 -- Research Misconduct -- 1.10.5 -- Fraud -- 1.10.6 -- Notable Examples of Fraudâ#x80;#x94;Biomedical Researchers Behaving Badly -- 1.10.6.1 -- MMR Vaccine: Andrew Wakefieldâ#x80;#x94;Royal Free Hospital -- 1.10.6.2 -- Embryonic Stem Cells: Hwang Woo-Sukâ#x80;#x94;Seoul National University -- 1.10.6.3 -- Environment and Human Behavior: Diederik Stapelâ#x80;#x94;Tilburg University
  table of contents: ""1.10.6.4 -- Stimulus-Triggered Acquisition of Pluripotency (STAP): Haruko Obokataâ#x80;#x94;RIKEN Institute""
  note: edited by Michael Williams, Michael J. Curtis, Kevin Mullane.
  note: Includes bibliographical references and index.
  subject:
    topic: Medical sciences
    topic: Research
  subject:
    topic: Biology
    topic: Research
  subject:
    topic: Biomedical Research
  subject:
    topic: Sciences de la santé
    topic: Recherche
  subject:
    topic: Biologie
    topic: Recherche
  subject:
    topic: HEALTH & FITNESS
    topic: Diseases
    topic: General
  subject:
    topic: MEDICAL
    topic: Clinical Medicine
  subject:
    topic: MEDICAL
    topic: Diseases
  subject:
    topic: MEDICAL
    topic: Evidence-Based Medicine
  subject:
    topic: MEDICAL
    topic: Internal Medicine
  subject:
    topic: Biology
    topic: Research
  subject:
    topic: Medical sciences
    topic: Research
  classification: R850
  classification: 616
  classification: W 20.5
  related item:
    title info:
      title: Research in the biomedical sciences
    origin info:
      publisher: London : Academic Press, [2018]
    identifier: (OCoLC)1005701248
  related item:
    title info:
      title: Research in the biomedical sciences
    origin info:
      publisher: London : Academic Press, [2018]
    identifier: (OCoLC)962890334
  identifier: 9780128047262
  identifier: 0128047267
  identifier: 9780128047255
  identifier: 0128047259
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: N$T
    record creation date: 171010
    record change date: 20260327152433.8
    record identifier: in00005762452
    language of cataloging:
      language term: eng