rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: rewiring brain
    sub title: a computational approach to structural plasticity in the adult brain
  name:
    name part: Van Ooyen, Arjen
    role:
      role term: editor.
  name:
    name part: Butz-Ostendorf, Markus
    role:
      role term: editor.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: abstract or summary
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists.
  table of contents: Front Cover; The Rewiring Brain; Copyright Page; Contents; List of Contributors; Editorial; 1 Introduction; 2 Experimental Background; 3 Homeostatic Structural Plasticity; 4 Structural Plasticity and Connectivity; 5 Structural Plasticity and Learning and Memory; 6 Neurogenesis-Related Structural Plasticity; 7 Structural Plasticity and Pathology; 8 Outlook; References; I. Experimental Background; 1 Structural Plasticity and Cortical Connectivity; 1 Introduction; 2 The Role of Structural Synaptic Plasticity in Hebb's Theory of Cell Assemblies.
  table of contents: 3 Structural Plasticity Following Enriched Experience4 Structural Plasticity Following Sensory Deprivation or Stimulation; 5 Structural Plasticity in Learning and Memory; 6 Structural Plasticity and Long-Term Functional Synaptic Plasticity; 7 Activity-Dependent and -Independent Structural Synaptic Plasticity; 8 Structural Plasticity and Cortical Connectivity; 8.1 Large-Scale Structural Plasticity; 8.2 Microscopic Structural Plasticity and Cortical Connectivity; 8.3 Mechanisms of Microscopic Structural Plasticity Influencing Cortical Connectivity; 9 Future Perspectives; Acknowledgments.
  table of contents: 4 Dendritic Arbor Remodeling5 Dendritic Spine Plasticity; 6 Perspectives and Future Directions; 6.1 Technological Developments; 6.2 Minimizing the Dark Side of Structural Plasticity Through Intelligent Intervention; 6.3 Computational Modeling Studies; References; 4 Is Lesion-Induced Synaptic Rewiring Driven by Activity Homeostasis?; 1 Introduction; 2 Current View and Limitations; 2.1 Current View; 2.2 Limitations; 3 Homeostatic Structural Plasticity; 3.1 Hypothesis; 3.2 Expectations; 4 In Vitro Indications for Homeostatic Structural Plasticity; 4.1 Dendritic Spines.
  table of contents: 4.2 Dendrite and Axon Outgrowth4.3 Minimum Activity for Spine Formation and Neurite Outgrowth; 5 In Vivo Indications for Homeostatic Structural Plasticity; 5.1 Visual Cortex; 5.2 Barrel Cortex; 5.3 Stroke; 6 Experimental Testing of Homeostatic Structural Plasticity; 6.1 Growth Curves; 6.2 Activity Restoration; 7 Discussion; 7.1 Relation to Other Forms of Plasticity; 7.2 Cortical Remapping; 7.3 Maladaptive Responses; 7.4 Neurodegeneration; 7.5 Neurological Therapy; 7.6 Computational Modeling; 8 Conclusion; References; II. Homeostatic Structural Plasticity.
  note: edited by Arjen van Ooyen, VU University Amsterdam, Amsterdam, the Netherlands, Markus Butz-Ostendorf, Biomax Informatics AG, Planegg, Germany.
  note: Includes index.
  note: Includes bibliographical references and index.
  subject:
    topic: Brain
    topic: Physiology
  subject:
    topic: Cognitive neuroscience
  subject:
    topic: Neuroplasticity
  subject:
    topic: Computer simulation
  subject:
    topic: Digital computer simulation
  subject:
    topic: Neuronal Plasticity
    topic: physiology
  subject:
    topic: Brain
    topic: physiology
  subject:
    topic: Nervous System Diseases
    topic: physiopathology
  subject:
    topic: Computer Simulation
  subject:
    topic: Neuronal Plasticity
  subject:
    topic: Cerveau
    topic: Physiologie
  subject:
    topic: Neurosciences cognitives
  subject:
    topic: Plasticité neuronale
  subject:
    topic: Simulation par ordinateur
  subject:
    topic: simulation
  subject:
    topic: MEDICAL
    topic: Physiology
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Human Anatomy & Physiology
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Neuroscience
  subject:
    topic: Digital computer simulation
  subject:
    topic: Computer simulation
  subject:
    topic: Brain
    topic: Physiology
  subject:
    topic: Cognitive neuroscience
  subject:
    topic: Neuroplasticity
  classification: QP376
  classification: 612.82
  classification: 2018 D-110
  classification: WL 102
  related item:
    title info:
      title: Rewiring brain
    origin info:
      publisher: London ; San Diego, CA : Academic Press, 2017
    identifier: (OCoLC)962355137
  identifier: 9780128038727
  identifier: 0128038721
  identifier: 9780128037843
  identifier: 0128037849
  identifier: 40027947197
  identifier: 2017936517
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: N$T
    record creation date: 170628
    record change date: 20260327152231.2
    record identifier: in00005762218
    language of cataloging:
      language term: eng