rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Translational immunotherapy of brain tumors
  name:
    name part: Sampson, John H.
    role:
      role term: editor.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  genre: Internet Resources.
  origin info:
    place:
      place term: enk
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  table of contents: Front Cover; TRANSLATIONALIMMUNOTHERAPY OFBRAIN TUMORS; TRANSLATIONALIMMUNOTHERAPYOF BRAINTUMORS; Copyright; Contents; List of Contributors; Introduction to Translational Immunotherapy for Brain Tumors; TRANSLATIONAL IMMUNOTHERAPY FOR BRAIN TUMORS SUMMARY; PRIMER ON MALIGNANT GLIOMAS; THE POTENTIAL OF CANCER IMMUNOTHERAPY; CHALLENGES OF BRAIN TUMOR IMMUNOTHERAPY; CHAPTER OVERVIEW; References; I -- IIMMUNOLOGICALFEATURES OF BRAINTUMORS; 1 -- An Introduction to Immunotherapy in the Treatment of Brain Tumors; INTRODUCTION; THE IMMUNE RESPONSE; IMMUNE TOLERANCE
  table of contents: UNIQUE ASPECTS OF THE CENTRAL NERVOUS SYSTEM IMMUNE RESPONSEThe Blood-Brain Barrier; The CNS Lymphatic System; Antigen Presentation in the CNS; CANCER IMMUNOTHERAPIES; References; 2 -- Immune Constitution of Patients With Brain Tumors; BACKGROUND AND DISCOVERY; CURRENT UNDERSTANDING: ANALYZING SYSTEMIC IMMUNE DYSFUNCTION; Lymphopenia; Lymphocyte Dysfunction; Regulatory T Cells; CURRENT UNDERSTANDING: ANALYZING THE TUMOR; Cytokine Dysregulation; Signal Transducer and Activator of Transcription-3; Indoleamine 2,3 Dioxygenase; CLINICAL OPPORTUNITIES
  table of contents: Countering T Cell Dysfunction: Immune Checkpoint BlockadeCountering Regulatory T Cells and Lymphopenia; Countering Cytokine Dysregulation; Countering Tumor STAT3 and IDO Expression; CONCLUSION; References; 3 -- The Role of Regulatory T Cells and Indoleamine-2,3-dioxygenase in Brain Tumor Immunosuppression; BACKGROUND AND DISCOVERY; ORIGIN OF TREGS; FUNCTION OF TREGS; TREGS IN THE CANCER IMMUNITY CYCLE; TREGS AND GLIOMA; TRYPTOPHAN CATABOLISM IN IMMUNITY AND IN CANCER; IDO1, IDO2, AND TDO; THE AHR; MECHANISMS OF IMMUNE REGULATION BY THE IDO PATHWAY; THE IDO PATHWAY IN CANCER AND IN GLIOMA
  table of contents: TARGETING TREGS IN PRECLINICAL MODELTARGETING IDO IN PRECLINICAL MODELS; CLINICAL TRIAL DATA; CONCLUSION; References; 4 -- The Role of Myeloid-Derived Suppressor Cells in Immunosuppression in Brain Tumors; BACKGROUND AND DISCOVERY OF THE MYELOID CELL; MDSCs in Mice; MDSCs in Humans; MDSC Activation, Proliferation, Migration, and Expansion; Suppressive Mechanisms Mediated by MDSCs; Suppression via Arg1 and iNOS; Suppression via Reactive Oxygen Species; Suppression via Peroxynitrite; Other Immunosuppressive Mechanisms; MDSCs in Glioma Development; PRECLINICAL DATA: TARGETING THE MDSC POPULATION
  note: edited by John H. Sampson.
  note: Includes index.
  note: Includes bibliographical references and index.
  subject:
    topic: Brain
    topic: Tumors
    topic: Immunotherapy
  subject:
    topic: Brain Neoplasms
    topic: therapy
  subject:
    topic: Cerveau
    topic: Tumeurs
    topic: Immunothérapie
  subject:
    topic: HEALTH & FITNESS
    topic: Diseases
    topic: General
  subject:
    topic: MEDICAL
    topic: Clinical Medicine
  subject:
    topic: MEDICAL
    topic: Diseases
  subject:
    topic: MEDICAL
    topic: Evidence-Based Medicine
  subject:
    topic: MEDICAL
    topic: Internal Medicine
  classification: RC280.B7
  classification: 616.99/48106
  classification: 2017 D-843
  classification: WL 358
  related item:
    title info:
      title: Translational immunotherapy of brain tumors
    origin info:
      publisher: London, United Kingdom : Academic Press, an imprint of Elsevier, 2017
    identifier: (OCoLC)959874904
  identifier: 9780128026250
  identifier: 0128026251
  identifier: 9780128024201
  identifier: 0128024208
  identifier: 2017285243
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: N$T
    record creation date: 170210
    record change date: 20260327151629.6
    record identifier: in00005761651
    language of cataloging:
      language term: eng