rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Dynemicin A
  name:
    name part: Best, Daniel.
    role:
      role term: creator
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: xx
    date issued: 2016
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (146)
  abstract: Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis. Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs.
  subject:
    topic: Antineoplastic antibiotics
  subject:
    topic: Antibiotics, Antineoplastic
  subject:
    topic: Antibiotiques antinéoplasiques
  subject:
    topic: MEDICAL
    topic: Pharmacology
  subject:
    topic: Antineoplastic antibiotics
  classification: RC271.A65
  classification: 615.7
  classification: QV 269
  related item:
    identifier: (OCoLC)945105382
  identifier: 0081010869
  identifier: 9780081010860
  identifier: 1785481509
  identifier: 9781785481505
  identifier: 934610 MIL
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: IDEBK
    record creation date: 160701
    record change date: 20260327150629.0
    record identifier: in00005760630
    language of cataloging:
      language term: eng