Epigenomics in health and disease /

Reviews the technologically-driven study of the oganismal epigenome and associated translational impacts on future prognosis, diagnosis and therapies of disease. With next-generation sequencing technologies shaping our current knowledge of the role of epigenetics in normal development, aging, and di...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Fraga, Mario F., Fernández, Agustín F.
Format: eBook
Language:English
Published: London : Academic Press, 2015, ©2016.
Series:Translational epigenetics series.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • The role of the genetic code in the DNA methylation landscape formation / Holger Heyn
  • DNA methylation microarrays / Marina Bibikova
  • Ultra-deep sequencing of bisulfite-modified DNA / Tingting Qin, Yongseok Park, Maria E. Figueroa and Maureen A. Sartor
  • Bioinformatics tools in epigenomics studies / Gustavo F. Bayón, Augustín F. Fernández and Mario F. Fraga
  • Noncoding RNA regulation of health and disease / Nicolas Léveillé, Carlos A. Melo and Sonia A. Melo
  • Genome-wide DNA methylation changes during aging / Kevin C. Johnson and Brock C. Christensen
  • The dynamics of histone modifications during aging / Anthony J Bainor and Gregory David
  • Epigenomic studies in epidemiology / Valentina Bollati, Valeria Motta, Simona Iodice and Michele Carugno
  • The DNA methylomes of cancer / Renée Beekman, Marta Kulis and José Ignacio Martín-Subero
  • Genome-wide epigenetic studies in neurologic diseases / Ashwin Woodhoo
  • Epigenetic deregulation in autoimmune disease / Damiana Álvarez-Errico and Esteban Ballestar
  • Genome-wide DNA and histone modification studies in metabolic disease / Charlotte Ling and Tina Rönn
  • Clinical applications of epigenomics / Michael A. McDevitt.