rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: enzymes
    part number: Volume 37
    part name: Mechanism of the anticancer effect of phytochemicals
  title info:
    title: Mechanism of the anticancer effect of phytochemicals
  name:
    name part: Bathaie, S. Zahra
    role:
      role term: editor.
  name:
    name part: Tamanoi, Fuyuhiko
    role:
      role term: editor.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: mau
    date issued: 2015
    edition: First edition.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xiii, 262 pages) : illustrations.
  abstract: Volume 37 will provide details on the major chemical constituents of medicinal plants and their mechanism of action as the anticancer compounds. This special issue, in addition to the previous volume (volume 36 of the Enzyme series was on the topic of Natural Products and Cancer Signaling Targets: Isoprenoids, Polyphenols and Flavonoids), will highlight the significant advance made in the field in elucidating mechanisms of anticancer effect of the major phytochemicals. Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field.
  table of contents: ""Front Cover""; ""Mechanism of the Anticancer Effect of Phytochemicals""; ""Copyright""; ""Contents""; ""Contributors""; ""Preface""; ""Chapter One: How Phytochemicals Prevent Chemical Carcinogens and/or Suppress Tumor Growth?""; ""1. Introduction""; ""2. Phytochemicals Application in Chemoprevention Strategies""; ""2.1. Blocking Initiation/Reversing Promotion""; ""2.2. Activating Phase II Detoxifying Enzymes""; ""2.3. Prooxidant/Antioxidant Activities""; ""2.4. Protection Against Radiation""; ""2.5. Alteration in Signaling Pathways""; ""2.6. Effect on Cell-Cell Adhesion Machinery""
  table of contents: ""2.7. Induction of Epigenetic Changes""""3. Phytochemicals Usage as Chemotherapeutic""; ""3.1. Inhibition of Enzymes""; ""3.1.1. Inhibition of Topoisomerases I or II""; ""3.1.2. Effect on Telomerase""; ""3.1.3. Other Enzymes""; ""3.2. Direct Binding to Biomacromolecules""; ""3.3. Epigenetic Alteration/Chromatin Modification""; ""3.3.1. Histone Modifications: Acetylation/Deacetylation and Methylation/Demethylation""; ""3.3.2. DNA Methylation Status""; ""3.4. RNA Modulation""; ""3.5. Autophagy and UPR68""; ""3.6. Apoptosis Induction""; ""3.7. Cell Cycle Arrest""
  table of contents: ""3.8. Inhibiting Angiogenesis""""3.9. Adjuvant/Combinatorial Therapy""; ""4. Summary""; ""References""; ""Chapter Two: Quercetin and Tryptanthrin: Two Broad Spectrum Anticancer Agents for Future Chemotherapeutic Interventions""; ""1. Introduction""; ""2. Quercetin""; ""2.1. Source""; ""2.2. Biosynthesis""; ""2.3. Structure and Antioxidative Property""; ""2.4. Properties""; ""2.4.1. Antioxidant Property""; ""2.4.2. Free Radical Scavenging Activity""; ""2.4.3. Nitric Oxide Inhibitory Action""; ""2.4.4. Inhibition of Xanthine Oxidase""; ""2.4.5. Interaction with Other Enzyme Systems""
  table of contents: ""2.5. Pharmacokinetics""""2.6. Role as an Anticancer Agent""; ""2.6.1. Cell Cycle Regulation""; ""2.6.2. QuercetinÂ?s Effect on Apoptosis""; ""2.6.3. Inhibition of Pathways Involved in Tumor Growth and Invasiveness""; ""2.7. QuercetinÂ?s Role as an Anti-Inflammatory Agent""; ""2.8. QuercetinÂ?s Influence on p53""; ""2.9. QuercetinÂ?s Nontoxicity Against Normal Cells""; ""2.10. QuercetinÂ?s Action Against Chemical-Induced Tumor and Xenograft""; ""2.11. Synergism with Other Drugs""; ""2.12. Clinical Study""; ""3. Tryptanthrin""; ""3.1. Chemistry""; ""3.2. Source""; ""3.3. Medicinal Value""
  table of contents: ""3.4. Cytotoxic and Anticancer Properties of Tryptanthrin""""3.5. Structural Modification of Tryptanthrin for Increasing its Bioactivity""; ""3.6. Tryptanthrin Prevents Development of Cancer by the Inhibition of Various Molecular Events""; ""3.6.1. Antioxidant Activity""; ""3.6.2. Anti-Inflammatory Activity""; ""3.7. Angiogenesis""; ""3.8. Toxicological Analysis""; ""4. Conclusion""; ""Acknowledgement""; ""References""; ""Chapter Three: Potential Anticancer Properties and Mechanisms of Action of Withanolides""; ""1. Introduction""; ""2. Reactive Oxygen Species Signaling""
  note: edited by S. Zahra Bathaie and Fuyuhiko Tamanoi.
  note: Includes bibliographical references and indexes.
  subject:
    topic: Phytochemicals
    topic: Therapeutic use
  subject:
    topic: Phytochemicals
    topic: Molecular aspects
  subject:
    topic: Antineoplastic agents
  subject:
    topic: Phytonutrients
  subject:
    topic: Phytochemicals
  subject:
    topic: Antineoplastic Agents
  subject:
    topic: Composés phytochimiques
    topic: Emploi en thérapeutique
  subject:
    topic: Anticancéreux
  subject:
    topic: Phytonutriments
  subject:
    topic: MEDICAL
    topic: Pharmacology
  subject:
    topic: Phytonutrients
  subject:
    topic: Antineoplastic agents
  subject:
    topic: Phytochemicals
    topic: Molecular aspects
  subject:
    topic: Phytochemicals
    topic: Therapeutic use
  classification: RS164
  classification: 615.3/21
  classification: QV 269
  related item:
    title info:
      title: Enzymes. Volume 37, Mechanism of the anticancer effect of phytochemicals
    origin info:
      publisher: Waltham, MA : Academic Press is an imprint of Elsevier, 2015
      edition: First edition.
    identifier: (OCoLC)911073512
  related item:
    title info:
      title: Enzymes ; volume 37
  identifier: 9780128038772
  identifier: 0128038772
  identifier: 9780128038765
  identifier: 0128038764
  identifier: 823997 MIL
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: N$T
    record creation date: 150825
    record change date: 20260326213731.5
    record identifier: in00005759512
    language of cataloging:
      language term: eng