rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: DNA methylation and complex human disease
  name:
    name part: Neidhart, Michel
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: cau
    date issued: 2016
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylati.
  table of contents: ""Front Cover""; ""DNA Methylation and Complex Human Disease""; ""Copyright Page""; ""Contents""; ""Preface""; ""About the Author""; ""1 DNA Methylation â€? Introduction""; ""1.1 Epigenetics""; ""1.2 Histone Modifications""; ""1.2.1 Histone Acetylation and Deacetylation""; ""1.2.2 Histone Methylation""; ""1.3 DNA Methylation""; ""1.3.1 DNA Methyltransferases""; ""1.4 Methyl-Binding Domain Proteins""; ""1.5 DNA Demethylation""; ""1.6 DNA Hydroxymethylation""; ""1.7 Differentially Methylated Regions""; ""1.8 Nutriepigenomics""; ""References""
  table of contents: ""2 DNA Methylation and Epigenetic Biomarkers in Cancer""""2.1 Introduction""; ""2.1.1 Diagnosis Biomarkers""; ""2.1.2 Progression Biomarkers""; ""2.1.3 Predictive Biomarkers""; ""2.1.4 Discovery of Novel Biomarkers""; ""2.2 Cancerogenesis""; ""2.3 Epimutations in Cancer""; ""2.3.1 Esophageal Adenocarcinoma""; ""2.3.2 Gastric Cancer""; ""2.3.3 Colorectal Carcinoma""; ""2.3.4 Lynch Syndrome""; ""2.3.5 Endometrial and Ovarian Cancers""; ""2.3.6 Lung Cancer""; ""2.3.7 Glioblastoma""; ""2.3.8 Hematopoietic Cancers""; ""2.4 Conclusion""; ""References""
  table of contents: ""3 DNA Methylation and Epigenetic Biomarkers in Non-Neoplastic Diseases""""3.1 Introduction""; ""3.2 Autoimmunity""; ""3.2.1 Type 1 Diabetes""; ""3.2.2 Rheumatoid Arthritis""; ""3.2.3 Systemic Lupus Erythematosis""; ""3.2.4 Inflammatory Bowel Disease, Crohnâ€?s Disease, and Ulcerative Colitis""; ""3.3 Metabolic Diseases""; ""3.3.1 Type 2 Diabetes""; ""3.3.2 Heart Failure""; ""3.4 Developmental Diseases""; ""3.4.1 Imprinting Disorders""; ""3.4.2 Arrhythmia""; ""3.5 Psychiatric Diseases""; ""3.5.1 Major Depressive Disorder""; ""3.5.2 Schizophrenia""; ""3.6 Conclusion""; ""References""
  table of contents: ""4 DNA Methylation and Environmental Factors""""4.1 Introduction""; ""4.2 Impact of the Environment in Early Life""; ""4.2.1 Genomic Imprinting""; ""4.2.2 Beckwith-Wiedemann Syndrome""; ""4.2.3 Assisted Reproductive Technologies""; ""4.2.4 Large Offspring Syndrome""; ""4.3 Nutritional Factors""; ""4.3.1 Gestational Maternal Nutritional Factors""; ""4.3.2 Nutritional Deficiencies""; ""4.4 Adverse Environmental Factors""; ""4.4.1 Environmental Toxicants""; ""4.4.2 Ethanol Consumption""; ""4.4.3 Smoking""; ""4.5 Immune Activation""; ""4.5.1 Asthma and Allergy""; ""4.5.2 Bacterial Infections""
  table of contents: ""4.5.3 Viral Infections""""4.6 Maternal Mood and Experience in Early Life""; ""4.7 Physical Exercise""; ""4.8 Conclusion""; ""References""; ""5 DNA Methylation and Epidemiology""; ""5.1 Introduction""; ""5.2 Endocrine Disrupting Chemicals""; ""5.2.1 Bisphenol-A""; ""5.2.2 Diethylstillbestrol""; ""5.2.3 Cadmium""; ""5.3 Epigenomics and Breast Cancer""; ""5.3.1 RASSF1A""; ""5.3.2 P16/CDKN2A""; ""5.4 Tobacco Smoking""; ""5.4.1 F2RL3, Smoking, and Cardiovascular Diseases""; ""5.4.2 RUNX3, Smoking, Low Birth Weight, and Lung Carcinomas""; ""5.4.3 AHRR, Smoking, and Lung Metastasis""
  note: Michel Neidhart.
  note: Includes bibliographical references and index.
  subject:
    topic: DNA
    topic: Methylation
  subject:
    topic: Medical genetics
  subject:
    topic: DNA Methylation
  subject:
    topic: Genetics, Medical
  subject:
    topic: ADN
    topic: Méthylation
  subject:
    topic: Génétique médicale
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Biochemistry
  subject:
    topic: DNA
    topic: Methylation
  subject:
    topic: Medical genetics
  classification: QP624.5.M46
  classification: 572.8/645
  classification: QU 58.5
  related item:
    title info:
      title: DNA methylation and complex human disease
    name:
      name part: Neidhart, Michel.
    origin info:
      publisher: Amsterdam : Elsevier, 2016
    identifier: (OCoLC)885228983
  identifier: 9780127999203
  identifier: 0127999205
  identifier: 9780124201941
  identifier: 0124201946
  identifier: 2017287047
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: N$T
    record creation date: 150818
    record change date: 20260326213730.9
    record identifier: in00005759505
    language of cataloging:
      language term: eng