http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Protein kinase inhibitors in research and medicine
1 online resource (xii, 241 pages, 42 unnumbered pages of plates) : illustrations (chiefly color)
Catalytic mechanisms and regulation of protein kinases / Zhihong Wang and Philip A. Cole -- A structural atlas of kinases inhibited by clinically approved drugs / Qi Wang, Julie A. Zorn, and John Kuriyan -- Fragment-based approaches to the discovery of kinase inhibitors / Paul N. Mortenson, Valerio Berdini, and Marc O'Reilly -- Targeting protein kinases with selective and semipromiscuous covalent inhibitors / Rand M. Miller and Jack Taunton -- The resistance tetrad : amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles / Fiona P. Bailey, Veselin I. Andreev, and Patrick A. Eyers -- FLiK : a direct-binding assay for the identification and kinetic characterization of stabilizers of inactive kinase conformations / Jeffrey R. Simar and Daniel Rauh -- Discovery of allosteric Bcr-Abl inhibitors from phenotypic screen to clinical candidate / Nathanael S. Gray and Doriano Fabbro -- The logic and design of analog-sensitive kinases and their small molecule inhibitors / Michael S. Lopez, Joseph I. Kliegman, and Kevan M. Shokat.
Includes bibliographical references and indexes.