Methods of animal experimentation. Volume II /
Methods of Animal Experimentation, Volume II, provides information on the most common methods for using animals as tools in the search for new biological knowledge. The techniques described will facilitate the most efficient use of research animals and provide guidelines for their utmost comfort and...
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| Format: | eBook |
| Language: | English |
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New York :
Academic Press,
1965.
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| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover; Methods of Animal Experimentation; Copyright Page; List of Contributors; Preface; Table of Contents; Contents of Volume I; Introduction; CHAPTER 1. Radiation Hygiene; I. The Nature and Assessment of Ionizing Radiation Effects; II. Health Physics; APPENDIX; RECOMMENDED READING; REFERENCES; CHAPTER 2. Use of Ionizing Radiation for Measuring Biological Phenomena; I. Introduction; II. Laboratory Design; III. Handling of Radioisotopes in the Animal Colony; IV. Administration of Radiation or Radioisotopes to the Experimental Animal; V. Collection of Samples; VI. Uses of Radioisotopes.
- GENERAL REFERENCESREFERENCES; CHAPTER 3. Tumor Transplantation; I. Introduction; II. History and Biological Properties of 38 Transplantable Mouse, Rat, Hamster, and Chicken Tumors; III. Techniques of Tumor Transplantation; IV. Importance of Uniform Inoculum; V. Importance of Animal Strain; VI. Inoculation Site; VII. Influence of Age and Sex; VIII. Influence of Health; IX. Influence of Pregnancy; X. Interval after Which Growth Becomes Apparent; XI. Comparative Growth Rate of the Malignant Cells; XII. Inoculation of Stationary or Receding Tumors.
- XIII. Spontaneous Regression of Transplantable TumorsXIV. Resistance to Reinoculation; XV. Frozen Storage of Transplantable Tumors; XVI. Summary; REFERENCES; CHAPTER 4. Parabiosis; I. Introduction; II. Methods; III. Blood and Fluid Exchange Between Parabiotic Rats; IV. Diseases of Parabiosis; REFERENCES; CHAPTER 5. Organ Transplantation; I. General Discussion of the Types of Problem That Can Be Investigated by Experimental Organ Transplantation; II. The Selection of Animals for Organ Transplantation; III. The Surgical Technique.
- IV. Methods of Assessment of Renal Function and Homograft Reaction in Animals with Renal TransplantsV. Summary; REFERENCES; CHAPTER 6. The Care and Use of Hibernating Mammals; I. Hibernation; II. Mammals That Hibernate; III. Types of Mammalian Hibernation; IV. Environmental Factors; V. Hibernation versus Hypothermia; VI. Estivation; VII. Choice of Animal for Research; IX. Care of Individual Species; X. Techniques for Use of Hibernators; ACKNOWLEDGMENTS; GENERAL REFERENCES; REFERENCES CITED; CHAPTER 7. High-Altitude Studies; I. Introduction; II. ""Natural"" High-Altitude Studies.
- III. ""Simulated"" High-Altitude StudiesIV. Conclusions; REFERENCES; CHAPTER 8. Care and Growth of Animals during Chronic Centrifugation; I. Introduction; II. Applications; III. General Considerations in the Design of Centrifuge Programs; IV. Specific Procedures Employed with Experimental Animals; V. Procedures of Measurement and Analysis; VI. Summary; ACKNOWLEDGMENTS; REFERENCES; CHAPTER 9. Controlled Exercise; I. Introduction; II. Methods of Inducing Controlled Exercise; III. Factors Influencing Controlled Exercise Results; IV. Factors Affecting Endurance; REFERENCES.