http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
1 online resource (xiii, 247 pages) : illustrations
Front Cover; The Thyroid Hormones; Copyright Page; Acknowledgements; Table of Contents; Introduction; CHAPTER 1. CHEMISTRY OF THYROXINE; ISOLATION OF THYROXINE; CONSTITUTION OF DESIODOTHYROXINE; CONSTITUTION OF THYROXINE; CHAPTER 2. THE IODINATED COMPOUNDS OF THE THYROID GLAND; DIIODOTYROSINE; MONOIODOTYROSINE; TRIIODOTHYRONINE; OTHER IODINATED THYRONINES; BIOLOGICAL SIGNIFICANCE OF THE IODOTHYRONINES; OTHER IODINATED AMINO ACIDS; CHAPTER 3. BIOSYNTHESIS OF THE THYROID HORMONES; (I) Formation of thyroxine from diiodotyrosine in vitro
(II) Biosynthesis of the thyroid hormones in vivo studied with radioactive iodine(III) Factors that influence thyroid function; (IV) The iodide-concentrating mechanism of the thyroid; (V) Organic binding of iodine in the thyroid, as influenced by the anterior pituitary; (VI) Iodine metabolism in the developing thyroid gland; (VII) Rate of secretion of the thyroid hormone into the circulation; CHAPTER 4. TRANSPORT OF THE THYROID HORMONE; (I) The circulating thyroid hormone; (II) The binding of thyroid hormones to serum proteins: thyroxine binding protein
(III) Thyroxine-binding by other serum protein, extravascular fluiss and tissue proteins(IV) Physiological significance of thyroxine-binding; (V) Methods used in the study of binding proteins; CHAPTER 5. PHYSIOLOGICAL ACTIONS OF THYROID HORMONES; (I) Calorigenic action and thermoregulation; (II) Growth, maturation and differentiation; (III) Effect on water and electrolyte metabolism; (IV) Effect on nitrogen and lipid metabolism; (V) Effect on the central nervous system; (VI) Effect on lactation; VII) Effect on the cardiovascular system and blood; (VIII) Other actions of the thyroid hormones
(IX) The latent period of action of thyroid hormones(X) Chemical structure and biological activity of substances related to thyroid hormones; CHAPTER 6. SOME CURRENT CONCEPTS OF THE MECHANISM OF ACTION OF THYROID HORMONES; (I) Earlier theories; (II) Current hypotheses; CHAPTER 7. EXTRATHYROIDAL DISTRIBUTION AND METABOLISM OF IODINE; (I) Extrathyroidal distribution and metabolism of iodide; (II) Distribution and metabolism of thyroid hormones; CHAPTER 8. BIOCHEMICAL PATHWAYS OF THYROID HORMONE METABOLISM; (I) Deiodination; (II) Phenolic oxidation and hydroxylation
(III) Conjugation of the phenolic group(IV) Rupture of the diphenyl ether linkage; (V) Oxidative deamination of the iodothyronines; (VI) Decarboxylation; CHAPTER 9. DISEASES OF THE THYROID; (I) NON-TOXIC Goitre; (II) Spontaneous myxoedema and lymphadenoid goitre; (III) Graves' disease; (IV) Thyroid cancer; APPENDIX; (I) Assay methods; (II) Some physical properties of thyroid hormones and related compounds; (Ill) Purification of thyroglobulin; REFERENCES; INDEX
by Rosalind Pitt-Rivers, M.Sc., Ph.D. London, F.R.S. and Jamshed R. Tata, M.Sc. Bangalore, Docteur ès Sciences, Paris ; with a chapter on diseases of the thyroid by W.R. Trotter, D.M. Oxon., B.M., B.Ch., M.R.C.P. London, University College Hospital Medical School, London.
Includes bibliographical references (pages 191-236)
International series of monographs on pure and applied biology