rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Stem cell bioprocessing
    sub title: for cellular therapy, diagnostics and drug development
  name:
    name part: Fernandes, Tiago G.
    role:
      role term: creator
  name:
    name part: Diogo, Maria Margarida.
  name:
    name part: Cabral, Joaquim S.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: Electronic books.
  genre: Internet Resources.
  origin info:
    place:
      place term: enk
    place:
      place term: Witney, UK
    publisher: Biohealthcare
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (250 pages)
  abstract: Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approachesEnvisages the use of stem cells in regenerative medicine and drug screening applicationsDiscusses the application of microscale techniques as a tool to perform basic stem cell biology studies.
  target audience: specialized
  note: Tiago G. Fernandes, Maria Margarida Diogo and Joaquim M.S. Cabral.
  subject:
    topic: Stem cells
  subject:
    topic: Biotechnology
    topic: Materials
  subject:
    topic: Bioreactors
  subject:
    topic: Cell separation
  subject:
    topic: Stem Cells
  subject:
    topic: Bioreactors
  subject:
    topic: Cell Culture Techniques
  subject:
    topic: Cell Separation
  subject:
    topic: Regenerative Medicine
    topic: methods
  subject:
    topic: Cellules souches
  subject:
    topic: Biotechnologie
    topic: Matériaux
  subject:
    topic: Bioréacteurs
  subject:
    topic: Cellules
    topic: Culture
    topic: Technique
  subject:
    topic: Cellules
    topic: Séparation
  subject:
    topic: Cell separation
  subject:
    topic: Bioreactors
  subject:
    topic: Biotechnology
    topic: Materials
  subject:
    topic: Stem cells
  classification: QH588.S83
  classification: 616/.02774
  classification: 2014 A-529
  classification: QU 325
  related item:
    title info:
      title: Biohealthcare Publishing series on pharma, biotech and biosciences ; no. 33
  identifier: 1907568883
  identifier: 9781907568886
  identifier: 9781306177016
  identifier: 1306177014
  identifier: 548952 MIL
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: CDX
    record creation date: 120911
    record change date: 20260326200134.5
    record identifier: in00005753839
    language of cataloging:
      language term: eng