rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Metal related neurodegenerative disease
  name:
    name part: Bhatia, Kailash
    role:
      role term: editor.
  name:
    name part: Schneider, Susanne A.
    role:
      role term: editor.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: ne
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xviii, 424 pages) : illustrations.
  abstract: This issue reviews the role of metals in neurodegenerative diseases; including Parkinson's and Huntington's disease; restless leg syndrome and NBIA disorders; and Wilson's disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented. This volume of International Review of Neurobiology brings together cutting-edge research on metal related neurodegenerative disease. It reviews the role of metals in neurodegenerative diseases, including Parkinson's and Huntington's disease; restless leg syndrome and NBIA disorders; and Wilson's disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented.
  table of contents: Front Cover; Metal Related Neurodegenerative Disease; Copyright; Contents; Contributors; Preface; Editorial: Metal-Related Neurological Disorders: Several New Genes and Better Understanding; Reference; Chapter One: The Relevance of Metals in the Pathophysiology of Neurodegeneration, Pathological Considerations; 1. Introduction; 2. The Role of Specific Metals in Neurodegeneration; 2.1. The role of iron; 2.1.1. Alzheimer disease; 2.1.2. Parkinson disease; 2.1.3. Multiple sclerosis; 2.1.4. Other neurodegenerative disorders; 2.2. The role of aluminum; 2.3. The role of copper
  table of contents: 2.4. The role of zinc2.5. The role of manganese; 3. Conclusions and Future Perspectives; References; Chapter Two: Pantothenate Kinase-Associated Neurodegeneration (PKAN) and PLA2G6-Associated Neurodegeneration (PLAN): Revi ...; 1. Introduction; 2. Pantothenate Kinase-Associated Neurodegeneration; 2.1. Clinical presentation; 2.1.1. Onset of clinical symptoms; 2.1.2. Clinical disease features; 2.1.3. Disease course; 2.2. Neuroimaging features in PKAN (Fig.2.1); 2.3. Neuropathological features of PKAN; 2.4. Molecular genetics of PKAN; 2.5. Pathophysiological disease mechanisms in PKAN
  table of contents: 2.6. Management of PKAN treatment2.6.1. Clinical assessment; 2.6.2. Treatment strategies; 2.6.3. Spasticity and dystonia; 2.6.4. Multidisciplinary team input; 2.6.5. New experimental therapies under consideration (see Chapter 7); 2.6.5.1. Iron chelation (see Chapter 7); 2.6.5.2. Pantothenate; 3. PLA2G6-Associated Neurodegeneration; 3.1. Clinical features of PLAN; 3.1.1. Disease onset; 3.1.2. Disease clinical features; 3.1.3. Disease course; 3.1.4. Electrophysiological investigations in PLAN; 3.2. Neuroimaging features of PLAN (Fig.2.3); 3.3. Neuropathological features of PLAN
  table of contents: 3.4. Molecular genetic features of PLAN3.5. Pathogenic disease mechanisms in PLAN; 3.6. Management of PLAN; 3.6.1. Clinical assessment; 3.6.2. Multidisciplinary team input; 3.6.3. New experimental therapies under consideration (see Chapter 7); 3.6.4. PLA2G6-dystonia parkinsonism; 3.6.5. Treatment strategies; 3.6.5.1. For INAD and atypical NAD; 4. Conclusion; Acknowledgments; References; Chapter Three: Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN); 1. Introduction; 2. Clinical Findings; 3. Neuroimaging; 4. Neuropathology; 5. Genetics; 6. Conclusion; Acknowledgments
  note: edited by Kailash P. Bhatia and Susanne A. Schneider.
  note: Includes bibliographical references and index.
  note: English.
  subject:
    topic: Nervous system
    topic: Degeneration
  subject:
    topic: Metal ions
    topic: Physiological effect
  subject:
    topic: Molecular neurobiology
  subject:
    topic: Chemistry, Metallurgic
  subject:
    topic: Ions métalliques
    topic: Effets physiologiques
  subject:
    topic: Neurobiologie moléculaire
  subject:
    topic: Métallurgie extractive
  subject:
    topic: Chemistry, Metallurgic
  subject:
    topic: Metal ions
    topic: Physiological effect
  subject:
    topic: Molecular neurobiology
  subject:
    topic: Nervous system
    topic: Degeneration
  classification: RC365
  classification: 616.8
  related item:
    title info:
      title: Metal related neurodegenerative disease
    origin info:
      publisher: Amsterdam ; Boston : Elsevier, AP, 2013
      edition: First edition.
    identifier: (DLC) 2013370373
  related item:
    title info:
      title: International review of neurobiology ; v. 110
  identifier: 9780124105027
  identifier: 0124105025
  identifier: 0124105351
  identifier: 9780124105355
  identifier: 2013370373
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: QCL
    record creation date: 131129
    record change date: 20260326195731.7
    record identifier: in00005753412
    language of cataloging:
      language term: eng