rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Advances in molecular toxicology
    part number: Volume 7
  name:
    name part: Fishbein, James C.
  name:
    name part: Heilman, Jacqueline M.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: ne
    place:
      place term: Amsterdam, Netherlands
    place:
      place term: Oxford, England
    publisher: Academic Press
    date issued: ©2013
    date issued: 2013
    edition: 1st ed.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xii, 241 pages) : illustrations
  abstract: Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.
  table of contents: Front Cover; Advances in Molecular Toxicology; Copyright; Contents; Contributors; Preface; Chapter One: AHR- and ER-Mediated Toxicology and Chemoprevention; 1. Introduction; 2. AHR Ligands; 2.1. Natural and/or dietary ligands; 2.2. Endogenous ligands; 3. Aryl Hydrocarbon Receptor; 3.1. Mechanism of AHR transactivation; 3.2. The nongenomic pathway; 3.3. Negative feedback regulation of AHR transactivation; 3.4. AHR-regulated signaling and toxicity; 3.5. Adverse human health effects of dioxin-like compounds; 3.6. Adaptive response pathway; 3.7. Developmental pathway
  table of contents: 6.2. Phenylenediamine arylamine xenobiotics7. Arylamine Drugs and Blood Dyscrasias; 7.1. Procainamide; 7.2. Aminoglutethimide; 7.3. Aminopyrine; 8. Diverting Toxic Arylamine Free Radical Generation to Detoxification: Importance of Free Radical Targets; 9. Mixtures Toxicology-Application to Arylamine Free Radicals; 10. Protein Radicals and Toxicity-Future Prospects; 11. Closing Remarks; References; Chapter Three: Genotoxicity of Polycyclic Aromatic Hydrocarbon Metabolites: Radical Cations and Ketones; 1. Introduction; 2. Exposure to PAHs; 3. Exposure Risks of PAH; 4. DNA Damage by PAH
  table of contents: 5. PAH Metabolism to DNA-Reactive Metabolites6. Diol-Epoxide Pathway; 7. The Radical Cation Pathway; 8. Depurinating PAH Adducts and AP Sites; 9. Mutagenesis Studies to Address PAH Radical Cations; 10. Evidence for AP Site Formation Due to Radical Cations; 11. Mutagenicity Studies with B[a]P Radical Cation Products; 12. The Quinone Pathway; 13. Exposure to OPAHs; 14. Biological Relevance of OPAH; 15. Conclusion; References; Chapter Four: Nitrogen Oxides Toxicology of the Aerodigestive Tract; 1. Introduction; 2. Chemistry of Reactive Oxygen and Nitrogen Oxide Species and the Scavengers
  note: edited by James C. Fishbein, Jacqueline M. Heilman.
  note: Included bibliographical references at the end of each chapters and index.
  note: English.
  subject:
    topic: Toxicology
  subject:
    topic: Molecular biology
  subject:
    topic: Toxicology
  subject:
    topic: Molecular Biology
  subject:
    topic: Toxicologie
  subject:
    topic: Biologie moléculaire
  subject:
    topic: toxicology
  subject:
    topic: molecular biology
  subject:
    topic: Molecular biology
  subject:
    topic: Toxicology
  classification: RA1211 .A383 2013eb
  classification: 615.9
  identifier: 9780444626554
  identifier: 0444626557
  identifier: 9780128022290
  identifier: 0128022299
  identifier: 9780444626455
  identifier: 044462645X
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: E7B
    record creation date: 130827
    record change date: 20260326195332.8
    record identifier: in00005753011
    language of cataloging:
      language term: eng