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Degradation rate of bioresorbable materials
Bioresorbable materials can be employed to provide significant advances in drug delivery systems and medical implants. The rate of material degradation is critical to performance of both implants and the controlled release of drugs. Degradation rate of bioresorbable materials addresses the practicalities of this subject in detail. Bioresorbable materials are extensively used for a wide range of biomedical applications from drug delivery to fracture fixation, and may remain in the body for weeks, months or even years. Accurately predicting and evaluating the degradation rate of these materials is critical to their performance and the controlled release of bioactive agents. Degradation rate of bioresorbable materials provides a comprehensive review of the most important techniques in safely predicting and evaluating the degradation rate of polymer, ceramic and composite based biomaterials. Part one provides an introductory review of bioresorbable materials and the.
Part 1 Introduction: An overview of bioresorbable materials -- The biological environment for bioresorbable materials. Part 2 Degradation mechanisms: Synthetic bioresorbable polymers -- Natural bioresorbable polymers -- Bioresorbable ceramics. Part 3 Bioresorption test methods: In-vitro physicochemical test methods to evaluate bioresorbability -- In-vitro biological test methods to evaluate bioresorbability -- In-vivo test methods to evaluate bioresorbability -- Modelling of the degradation processes for bioresorbable polymers. Part 4 Factors influencing bioresorption: Influence of processing, sterilisation and storage on bioresorbability -- Influence of porous structure on bioresorbability: Tissue engineering scaffolds. Part 5 Clinical application: Influence of clinical application on bioresorbability: Host response -- Scaffold and implant design: Considerations relating to characterization of biodegradibility and bioresorbability -- Drug release from bioresorbable materi.
Dr Fraser Buchanan is a Senior Lecturer in the School of Mechanical and Aerospace Engineering at Queens University Belfast. He is highly regarded for his expertise in developing and testing synthetic biomaterials.
Cambridge : Woodhead Publishing Ltd, 2008