The glutamate synapse as a therapeutical target : molecular organization and pathology of the glutamate synapse /
This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pat...
| Corporate Author: | |
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| Other Authors: | , , |
| Format: | eBook |
| Language: | English |
| Language Notes: | English. |
| Published: |
Amsterdam ; New York :
Elsevier Science,
1998.
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| Series: | Progress in brain research ;
v. 116. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed. A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation. |
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| Physical Description: | 1 online resource (xii, 462 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 0444827544 9780444827548 0080862411 9780080862415 |
| ISSN: | 0079-6123 ; 0079-6123 |