http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Recent advances in electron cryomicroscopy
1 online resource (vi, 132 pages) : illustrations (some color).
Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein gr.
Front Cover; Advances in Protein Chemistry and Structural Biology; Copyright Page; Contents; Chapter 1: From envelopes to atoms: The remarkable progress of biological electron microscopy; I. Introduction; II. Early History; III. Three-Dimensional Reconstruction; IV. Unstained Crystals; V. Rapid Freezing; VI. Helical Structures; VII. Amyloids; VIII. Icosahedral Viruses; IX. Single-Particle Analysis; X. Tomography; XI. Summary; References; Chapter 2: Present and future of membrane protein structure determination by electron crystallography; I. Introduction; II. The Membrane Environment.
III. Why Are There so Few Membrane Protein Structures?IV. Application of Electron Crystallography to Membrane Proteins; V. Atomic Structures by Electron Crystallography; VI. Advantages of Membrane Crystals; VII. Current Hurdles in Electron Crystallography; VIII. The Future of Electron Crystallography; References; Chapter 3: Single-particle applications at intermediate resolution; I. Introduction; II. Sample Preparation; III. Data Acquisition; IV. De Novo Model Building; V. Mapping of Subunits; VI. Building of Pseudo-Atomic Models.
VII. Integrating Structural Data at Intermediate Resolution with Other Biophysical InformationReferences; Chapter 4: Visualizing molecular machines in action: single-particle analysis with structural variability; I. Introduction; II. Two-Dimensional Image Analysis; III. Three-Dimensional Image Analysis; IV. Outlook; Acknowledgments; References; Author Index; Subject Index; Color Plates.
edited by Steven J. Ludtke and B.V. Venkataram Prasad.
Includes bibliographical references and indexes.
Advances in protein chemistry and structural biology : Recent Advances in Electron Cryomicroscopy, Part A
Advances in protein chemistry and structural biology ; v. 81