http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
1 online resource (xix, 1182 pages) : illustrations
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.
Molecular Organization of Cells -- Cell-ECM interactions In Repair and Regeneration -- Developmental Mechanisms of Regeneration -- The molecular basis of pluripotency in Principles of Regenerative Medicine -- How cells change their phenotype -- Scarless Wound Healing -- Somatic Cloning and Epigenetic Reprogramming in Mammals -- Engineered Proteins for Manipulating Gene Expression and Genome Sequence -- Genetic Approaches in Human Embryonic Stem Cells and Their Derivatives -- Embryonic Stem Cells: Derivation and Properties -- Alternate Sources of human embryonic stem cells -- Stem cells derived from amniotic fluid and placenta -- Induced Pluripotent stem cells -- Mesenchymal Stem cells Derived from Bone Marrow -- Multipotent adult progenitor cells -- Mesenchymal Stem cells -- Hepatic Stem Cells and Therapy -- Cardiac stem cells -- Skeletal muscle stem cells -- Stem Cells Derived from Fat -- Stem Cells Derived from Peripheral Blood -- Islet Cell Therapy and Pancreatic Stem Cells -- Regenerative Medicine for Diseases of the Retina -- Somatic cells: Growth and expansion potential of T Lymphocytes -- Mechanical Determinants of Tissue Development -- Morphogenesis and Morphogenic Proteins -- Physical stress as a factor in tissue growth and remodeling -- Intelligent Surfaces for Cell Sheet Engineering -- Applications of Nanotechnology in Regenerative Medicine -- Design Principles in Biomaterials and Scaffolds -- Natural Origin Materials- Processing, Modification and Performance -- Synthetic Polymers -- Collagen Based Scaffold Materials -- Hydrogels -- Surface Modification of Biomaterials -- Histogenesis in Three-Dimensional Scaffolds -- Biocompatibility and Bioresponse to biomaterials -- Mechano-inducible systems for stem cells -- Biomineralization and Bone Regeneration -- Cell therapy for blood substitutes -- Articular Cartilage -- Implantation of Myogenic Cells in Skeletal Muscles -- Clinical islet transplantation -- Fetal Tissues -- Engineering of Large Diameter Vessels -- Engineering of Small Diameter Vessels -- Cardiac Tissue -- Regenerative Medicine in the Cornea -- Alimentary Tract -- Extracorporeal Kidney Support -- Tissue Engineering of the Reproductive System -- Cartilage Tissue Engineering -- Functional Tissue Engineering of Ligament and Tendon Injuries -- Central Nervous System -- Peripheral Nervous System -- Tissue Engineering of Skin -- Tissue Engineering of the Respiratory Tree -- Ethical Considerations -- US Stem Cell Research Policy -- Overview of FDA Regulatory Process.
Includes bibliographical references and index.
1092522:10014602 Elsevier Science & Technology