Progress in nucleic acid research and molecular biology Vol. 42 /
PROG NUCLEIC ACID RES&MOLECULAR BIO V42.
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Language Notes: | English. |
| Published: |
San Diego :
Academic Press,
1992.
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| Series: | Progress in nucleic acid research and molecular biology.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover; Progress in Nucleic Acid Research and Molecular Biology, Volume 42; Copyright Page; Contents; Abbreviations and Symbols; Some Articles Planned for Future Volumes; Chapter 1. The Trp Repressor, A Ligand-Activated Regulatory Protein; I. Early (Pre-cloning) Research on the Trp Repressor, 1959-1980; II. The Molecular Cloning of trpR+ DNA Opened the Floodgates to Structure-Function Analysis; III. Nucleotide Sequence of trpR DNA; IV. Autogenous Transcriptional Regulation of the trpR Gene; V. Signal Strength of the trpR Promoter Relative to Other s70 Promoters of E. coli
- VI. Translation of trpR mRNA and the Effect of Temperature on Regulation in the trp SystemVII. The Primary Amino-acid Sequence of the Trp Repressor: General Overview; VIII. Engineered Systems for Overproduction of the Trp Repressor; Protein Purification Schemes; IX. Interaction of Tryptophan and Its Analogs with the Trp Repressor; Effects of Ligand Binding on Operator Affinity; X. Operator Targets Recognized by the Trp Holorepressor; XI. Structural Alterations in Trp Repressor Generated by Mutation or Proteolysis
- XII. The Trp Repressor as a Prototypical Member of Helix-turn-helix Family of DNA-Binding ProteinsXIII. Concluding Comments and Perspectives for Future Research on the Trp Repressor; References; Chapter 2. lmmunochemical Analyses of Nucleic Acids; I. Sources and Assays of Antibodies to Nucleic Acids; II. Antibodies to B-DNA; III. Antibodies to Single-stranded DNA; IV. Antibodies to Z-DNA; V. Variants of Double-stranded DNA: Poly(dA)·poly(dT) and "Bent" DNA; VI. Triplex DNA; VII. Antibodies to RNA·DNA; VIII. Branched-chain Ribonucleic Acid; IX. Cruciform DNA
- X. Antibodies to Modified Nucleosides and Nucleotides: BromodeoxyuridineXI. Antibodies to Alkylated Nucleic Acids; XII. Summary and Future Prospects; References; Chapter 3. Oligodeoxynucleotides as Antisense Inhibitors of Gene Expression; I. Oligonucleotides as Informational Drugs; II. Phosphorothioate Oligodeoxynucleotides; III. Inhibition of Translation in Cell-free Systems; IV. Cellular Uptake; V. Oncogene Inhibition; VI. Other Oligodeoxynucleotide Analogs; VII. Other Approaches; VIII. Conclusion; References
- Chapter 4. 5,6-Dihydropyrimidine Adducts in the Reactions and Interactions of Pyrimidines with ProteinsI. Approaches to Detect Michael Adducts of Pyrimidines; II. Enzyme Systems That Form Michael Adducts; References; Note Added in Proof; Chapter 5. RNA Replication of Plant Viruses Containing an RNA Genome; I. Overview; II. Replication of Brome Mosaic Virus RNA; III. Replication of Cowpea Chlorotic Mottle Virus RNA; IV. Replication of Cucumber Mosaic Virus RNA; V. Replication of Alfalfa Mosaic Virus RNA; VI. Replication of Turnip Yellow Mosaic Virus RNA