Progress in nucleic acid research and molecular biology Vol. 42 /

PROG NUCLEIC ACID RES&MOLECULAR BIO V42.

Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Cohn, Waldo E., Moldave, Kivie, 1923-
Format: eBook
Language:English
Language Notes:English.
Published: San Diego : Academic Press, 1992.
Series:Progress in nucleic acid research and molecular biology.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 0 0 |a Progress in nucleic acid research and molecular biology  |n Vol. 42 /  |c edited by Waldo E. Cohn, Kivie Moldave. 
260 |a San Diego :  |b Academic Press,  |c 1992. 
300 |a 1 online resource (xii, 292 pages) :  |b illustrations. 
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490 1 |a Progress in nucleic acid research and molecular biology 
504 |a Includes bibliographical references and index. 
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505 0 |a Front Cover; Progress in Nucleic Acid Research and Molecular Biology, Volume 42; Copyright Page; Contents; Abbreviations and Symbols; Some Articles Planned for Future Volumes; Chapter 1. The Trp Repressor, A Ligand-Activated Regulatory Protein; I. Early (Pre-cloning) Research on the Trp Repressor, 1959-1980; II. The Molecular Cloning of trpR+ DNA Opened the Floodgates to Structure-Function Analysis; III. Nucleotide Sequence of trpR DNA; IV. Autogenous Transcriptional Regulation of the trpR Gene; V. Signal Strength of the trpR Promoter Relative to Other s70 Promoters of E. coli 
505 8 |a VI. Translation of trpR mRNA and the Effect of Temperature on Regulation in the trp SystemVII. The Primary Amino-acid Sequence of the Trp Repressor: General Overview; VIII. Engineered Systems for Overproduction of the Trp Repressor; Protein Purification Schemes; IX. Interaction of Tryptophan and Its Analogs with the Trp Repressor; Effects of Ligand Binding on Operator Affinity; X. Operator Targets Recognized by the Trp Holorepressor; XI. Structural Alterations in Trp Repressor Generated by Mutation or Proteolysis 
505 8 |a XII. The Trp Repressor as a Prototypical Member of Helix-turn-helix Family of DNA-Binding ProteinsXIII. Concluding Comments and Perspectives for Future Research on the Trp Repressor; References; Chapter 2. lmmunochemical Analyses of Nucleic Acids; I. Sources and Assays of Antibodies to Nucleic Acids; II. Antibodies to B-DNA; III. Antibodies to Single-stranded DNA; IV. Antibodies to Z-DNA; V. Variants of Double-stranded DNA: Poly(dA)·poly(dT) and "Bent" DNA; VI. Triplex DNA; VII. Antibodies to RNA·DNA; VIII. Branched-chain Ribonucleic Acid; IX. Cruciform DNA 
505 8 |a X. Antibodies to Modified Nucleosides and Nucleotides: BromodeoxyuridineXI. Antibodies to Alkylated Nucleic Acids; XII. Summary and Future Prospects; References; Chapter 3. Oligodeoxynucleotides as Antisense Inhibitors of Gene Expression; I. Oligonucleotides as Informational Drugs; II. Phosphorothioate Oligodeoxynucleotides; III. Inhibition of Translation in Cell-free Systems; IV. Cellular Uptake; V. Oncogene Inhibition; VI. Other Oligodeoxynucleotide Analogs; VII. Other Approaches; VIII. Conclusion; References 
505 8 |a Chapter 4. 5,6-Dihydropyrimidine Adducts in the Reactions and Interactions of Pyrimidines with ProteinsI. Approaches to Detect Michael Adducts of Pyrimidines; II. Enzyme Systems That Form Michael Adducts; References; Note Added in Proof; Chapter 5. RNA Replication of Plant Viruses Containing an RNA Genome; I. Overview; II. Replication of Brome Mosaic Virus RNA; III. Replication of Cowpea Chlorotic Mottle Virus RNA; IV. Replication of Cucumber Mosaic Virus RNA; V. Replication of Alfalfa Mosaic Virus RNA; VI. Replication of Turnip Yellow Mosaic Virus RNA 
520 |a PROG NUCLEIC ACID RES&MOLECULAR BIO V42. 
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