http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Detection, Diagnosis and Vaccine Development
1 online resource (xvi, 577 pages : illustrations).
Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research. * Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions * Descibes the technologies that have contributed to our current knowledge about the Flaviviruses * Identifies the major problems faced in understanding the virus-host interactins that result in disease * An exhaustive compendium of current and past knowledge on the Flavivirus family.
Cover; Contents; Part 1: DIAGNOSIS AND SURVEILLANCE; Chapter 1. Serodiagnosis of Flaviviral Infections and Vaccinations in Humans; I. Introduction; II. Serodiagnostic Tests; III. Specimens; IV. Variations in Antibody Responses and Antibody Kinetics; V. Flavivirus Cross-Reactivity; VI. Properties of Serologic Tests; VII. Commercial Reagents, Test Kits, and Services; VIII. Diagnostic Strategies; References; Chapter 2. Molecular Amplification Assays for the Detection of Flaviviruses; I. Introduction.; II. Overview of Molecular Amplification Technologies; III. RT-PCR-Based Assays for Flaviviruses
IV. NASBA Assays for FlavivirusesV. Conclusion; References; Part 2: VIRUS EPIDEMIOLOGY, ECOLOGY, AND EMERGENCE; Chapter 3. Japanese Encephalitis; I. History; II. Clinical Description; III. Congenital Infection; IV. Animal Infections; V. Geographic Distribution; VI. Geographic Variation in Virus Strains; VII. Recent Changes in Geographic Range; VIII. Incidence and Prevalence; IX. Risk Factors; X. Ecological Factors in Disease Transmission; XI. Future Directions; References; Chapter 4. Epidemiology of St. Louis Encephalitis Virus; I. History; II. Clinical Description and Diagnosis
III. Geographical Distribution and Genetic VariationIV. Incidence and Prevalence.; V. Risk Factors; VI. Transmission Cycles; VII. Surveillance and Control; VIII. Impact of West Nile Virus Introduction; References; Chapter 5. West NileVirus: Epidemiology and Ecology in North America; I. Introduction; II. History; III. Clinical Description; IV. Geographic Distribution; V. Molecular Epidemiology; VI. Epidemiology and Epizootiology; VII. Ecology; VIII. Future Directions; References; Chapter 6. Dengue Epidemiology:Virus Epidemiology, Ecology,and Emergence; I. Introduction; II. History
III. Clinical DescriptionIV. Pathophysiology of Dengue Hemorrhagic Fever; V. Geographical Distribution; VI. Ecology of Dengue from a Biological Perspective; VII. Control of DF/DHF by Management of the Mosquito Vector; VIII. Future Prospects; IX. Conclusions; References; Chapter 7. Epidemiology and Ecology of Yellow Fever Virus; I. History; II. Classification; III. Ecology of Yellow Fever Virus; IV. Epidemiology of Yellow Fever Virus; V. Molecular Biology of Yellow Fever Virus; VI. Reemergence of Yellow Fever as a Major Public Health Problem; References; Chapter 8. Tick-Borne Flaviviruses
I. IntroductionII. Tick-Borne Encephalitis Virus, a Major Human Pathogen; III. Other Encephalitic Tick-Transmitted Flaviviruses; IV. Non-Encephalitic Mammalian Tick-Borne Flaviviruses; V. ''Hemorrhagic'' Tick-Borne Viruses; VI. Seabird Tick-Transmitted Viruses; VII. Control of Tick-Borne Encephalitis: Prospects for Live Attenuated Tick-Borne Encephalitis Virus Vaccines; VIII. Conclusions; References; Chapter 9. Epidemiology of Other Arthropod-Borne Flaviviruses Infecting Humans; I. Introduction; II. Other Flaviviruses of Africa; III. Other Flaviviruses of Europe
edited by Thomas J. Chambers, Thomas P. Monath.
Includes bibliographical references and index.