Current topics in membranes. Volume 48, Membrane permeability: 100 years since Ernest Overton /

Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Deamer, D. W., Kleinzeller, Arnošt, Fambrough, Douglas M.
Format: eBook
Language:English
Language Notes:English.
Published: San Diego : Academic Press, 1999.
Series:Current topics in membranes ; 48.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. Key Features * Provides an historical perspective of Overton's contributions to the theory of narcosis * Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion.
Physical Description:1 online resource (xviii, 423 pages) : illustrations.
Bibliography:Includes bibliographical references and index.
ISBN:1281713317
9781281713315
9786611713317
661171331X
0080585191
9780080585192