rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Chemokines
  name:
    name part: Handel, Tracy M.
    role:
      role term: editor.
  name:
    name part: Hamel, Damon J.
    role:
      role term: editor.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: cau
    date issued: 2009
    copyright date: 2009
    edition: 1st ed.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (parts A-B) : illustrations (color illustrations)
  abstract: The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a wide range of human diseases and infections, including certain types of cancer, inflammatory diseases, HIV, and malaria. This volume, focusing on chemokine structure and function, as well as signaling, and its companion volume (Methods in Enzymology volume 461, focusing chemokines as potential targets for disease intervention) provide a comprehensive overview and time-tested protocols in this field, making it an essential reference for researchers in the area. Along with its companion volume, provides a comprehensive overview of chemokine methods, specifically as related to potential disease therapy Gathers tried, tested, and trusted methods and techniques from top players in chemokine research Provides an essential reference on for researchers in the field.
  table of contents: Part A (v. 460) -- Part B (v. 461).
  table of contents: Front Cover; Methods In Enzymology: Chemokines, Part A; Copyright Page; Contents; Contributors; Preface; Section 1: Chemokines and Receptors in Disease; Chapter 1: Chapter One Chemokines in Human Breast Tumor Cells: Modifying Their Expression Levels and Determining Their Effects ; 1. Introduction; 2. Modifying Chemokine Expression in Breast Tumor Cells; 3. Establishment of Primary Local Breast Tumors and Pulmonary Metastases; Acknowledgments; References; Chapter 2: Chapter 2 CCR5 Pharmacology Methodologies and Associated Applications; 1. Introduction.
  table of contents: 2. CCR5 Signaling Assays and Application to Quantify and Characterize Ligand-Dependent Agonism, Antagonism, and Inverse Ag3. CCR5-Associated Ligand-Binding Assays; 4. Surrogate In Vitro Antiviral Assays; 5. CCR5 Site-Directed Mutagenesis and Ligand Docking Studies; 6. Non-HIV Indications-Associated Studies, Human CCR5 Knock-In Mice; References; Chapter 3: Chapter Three CXCR4 and Mobilization of Hematopoietic Precursors; 1. Introduction; 2. HSPC Mobilizing Agents that Target the CXCL12/CXCR4 Axis; 3. Donor Selection for HSPC Mobilization; 4. Flow Cytometric Enumeration of Mobilized HSPCs.
  table of contents: 5. Dosing and Kinetics of HSPC Mobilization by G-CSF and Plerixafor6. Flow Cytometric Analysis of CXCR4 Expression on Human CD34+ Subsets; 7. Functional Characterization of Mobilized HSPCs; 8. Concluding Remarks; Acknowledgment; References; Chapter 4: Double-Label Nonradioactive ; 1. Introduction; 2. Basic Protocol for ISH (Using Digoxygenin-Labeled Probe); 3. Comments; References; Chapter 5: Chapter Five Expression of Chemokines and Chemokine Receptors in Human Colon Cancer; 1. Introduction; 2. Materials and Methods; 3. Results; 4. Discussion; Acknowledgments; References.
  table of contents: Section II: Chemokine Related Proteins from PathogensChapter 6: Kaposi's Sarcoma Virally Encoded, G-Protein-Coupled Receptor: A Paradigm for Paracrine Transformation; 1. Introduction; 2. Cloning of vGPCR; 3. Assaying vGPCR Transforming Activity In Vitro; 4. vGPCR Transforming Activity In Vivo Using Xenograft Systems; 5. In Vivo Targeted Infection Using the TVA-RCAS System; 6. vGPCR-Induced Paracrine Transformation; 7. Characterization of vGPCR-Induced Molecular Signaling; 8. Evaluation of Activation of Second-Messenger-Generating Systems.
  table of contents: 9. Activation of Signal-Transducing Protein Kinases and Small GTPases10. Akt Kinase Assay; 11. vGPCR Stimulated Activation of Rac1-Pulldown Assays; 12. Western Blotting Using Phospho-Specific Antibodies; 13. Activation of Transcription Factors; 14. Global Changes in Gene Expression: Microarray Analysis; 15. NFkappaB Luciferase Assays; 16. NFkappaB Binding Assays; 17. Nuclear Translocation of NFkappaB; Acknowledgments; References; Chapter 7: Chapter 7 Pharmacological and Biochemical Characterization of Human Cytomegalovirus-Encoded G Protein-Coupled Recept; 1. Introduction.
  note: edited by Tracy M. Handel and Damon J. Hamel.
  note: Includes bibliographical references and index.
  subject:
    topic: Chemokines
  subject:
    topic: Chemokines
    topic: Physiological effect
  subject:
    topic: Chemokines
  subject:
    topic: Chimiokines
  subject:
    topic: Chimiokines
    topic: Effets physiologiques
  subject:
    topic: HEALTH & FITNESS
    topic: Diseases
    topic: General
  subject:
    topic: MEDICAL
    topic: Clinical Medicine
  subject:
    topic: MEDICAL
    topic: Diseases
  subject:
    topic: MEDICAL
    topic: Evidence-Based Medicine
  subject:
    topic: MEDICAL
    topic: Internal Medicine
  subject:
    topic: Chemokines
  subject:
    topic: chemokinen
  subject:
    topic: chemokines
  subject:
    topic: biochemische receptoren
  subject:
    topic: biochemical receptors
  subject:
    topic: chemische structuur
  subject:
    topic: chemical structure
  subject:
    topic: biochemie
  subject:
    topic: biochemistry
  subject:
    topic: Immunology
  subject:
    topic: Immunologie
  classification: QP601 .M49 v. 460-461
  classification: 616.079
  classification: QW 568 C5161 2009
  related item:
    title info:
      title: Chemokines
    origin info:
      publisher: San Diego, California : Academic Press/Elsevier, ©2009
      edition: 1st ed.
    identifier: (OCoLC)401458389
  related item:
    title info:
      title: Methods in enzymology ; v. 460
  related item:
    title info:
      title: Methods in enzymology ; v. 461
  identifier: 9780080956978
  identifier: 0080956971
  identifier: 9780080956961
  identifier: 0080956963
  identifier: 9780123749079
  identifier: 0123749077
  identifier: 9780128021958
  identifier: 0128021950
  identifier: 9780123749086
  identifier: 0123749085
  identifier: 9780123749079 (pt. B, v. 461)
  identifier: 0123749077 (pt. B, v. 461)
  identifier: 9780080956961 Ingram Content Group
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: CUS
    record creation date: 100609
    record change date: 20260326175126.5
    record identifier: in00005743038
    language of cataloging:
      language term: eng